Technology Process of C57H82N6O13
There total 19 articles about C57H82N6O13 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: Et3N / tetrahydrofuran; toluene / 0 - 20 °C
2: Et3N / tetrahydrofuran / 12 h / 20 °C
3: 78 percent / TFA / CH2Cl2 / 24 h / 20 °C
4: (i-Pr)2NEt; N,N'-bis(2-oxo-3-oxazolidinyl)phosphinic chloride / CH2Cl2 / 0 - 20 °C
5: TFA / CH2Cl2 / 15 h / 20 °C
6: N-methylmorpholine; N,N'-bis(2-oxo-3-oxazolidinyl)phosphinic chloride / CH2Cl2 / 12 h / 20 °C
7: TFA / CH2Cl2 / 12 h / 0 °C
With
4-methyl-morpholine; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
tetrahydrofuran; dichloromethane; toluene;
DOI:10.1021/jo001749v
- Guidance literature:
-
Multi-step reaction with 6 steps
1: Et3N / tetrahydrofuran / 12 h / 20 °C
2: 78 percent / TFA / CH2Cl2 / 24 h / 20 °C
3: (i-Pr)2NEt; N,N'-bis(2-oxo-3-oxazolidinyl)phosphinic chloride / CH2Cl2 / 0 - 20 °C
4: TFA / CH2Cl2 / 15 h / 20 °C
5: N-methylmorpholine; N,N'-bis(2-oxo-3-oxazolidinyl)phosphinic chloride / CH2Cl2 / 12 h / 20 °C
6: TFA / CH2Cl2 / 12 h / 0 °C
With
4-methyl-morpholine; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
tetrahydrofuran; dichloromethane;
DOI:10.1021/jo001749v
- Guidance literature:
-
Multi-step reaction with 7 steps
1: NaCNBH3; AcOH / methanol / 0 °C / pH 3 - 4
2: Et3N / tetrahydrofuran / 12 h / 20 °C
3: 78 percent / TFA / CH2Cl2 / 24 h / 20 °C
4: (i-Pr)2NEt; N,N'-bis(2-oxo-3-oxazolidinyl)phosphinic chloride / CH2Cl2 / 0 - 20 °C
5: TFA / CH2Cl2 / 15 h / 20 °C
6: N-methylmorpholine; N,N'-bis(2-oxo-3-oxazolidinyl)phosphinic chloride / CH2Cl2 / 12 h / 20 °C
7: TFA / CH2Cl2 / 12 h / 0 °C
With
4-methyl-morpholine; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; sodium cyanoborohydride; acetic acid; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jo001749v