Technology Process of 2-[(2-bromophenyl)(diisopropyl)silyl]pyrimidine
There total 3 articles about 2-[(2-bromophenyl)(diisopropyl)silyl]pyrimidine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
N-Bromosuccinimide; [bis(acetoxy)iodo]benzene; palladium diacetate;
In
1,2-dichloro-ethane;
at 50 ℃;
for 26h;
Concentration;
Temperature;
Time;
Reagent/catalyst;
Inert atmosphere;
Glovebox;
Schlenk technique;
DOI:10.1002/anie.201304884
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium phosphate; dirhodium tetraacetate / 1,4-dioxane / 4 h / 100 °C / Inert atmosphere
2: N-Bromosuccinimide; [bis(acetoxy)iodo]benzene; palladium diacetate / 1,2-dichloro-ethane / 60 °C / Inert atmosphere
With
dirhodium tetraacetate; potassium phosphate; N-Bromosuccinimide; [bis(acetoxy)iodo]benzene; palladium diacetate;
In
1,4-dioxane; 1,2-dichloro-ethane;
DOI:10.1021/ja3010545
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium phosphate; dirhodium tetraacetate / 1,4-dioxane / 80 - 100 °C / Inert atmosphere; Glovebox; Schlenk technique
2: [bis(acetoxy)iodo]benzene; palladium diacetate; N-Bromosuccinimide / 1,2-dichloro-ethane / 26 h / 50 °C / Inert atmosphere; Glovebox; Schlenk technique
With
dirhodium tetraacetate; potassium phosphate; N-Bromosuccinimide; [bis(acetoxy)iodo]benzene; palladium diacetate;
In
1,4-dioxane; 1,2-dichloro-ethane;
DOI:10.1002/anie.201304884