(2-(pyridin-2-yl)phenyl)bis(3-(trifluoromethyl)phenyl)phosphine oxide

Base Information

• Chemical Name: (2-(pyridin-2-yl)phenyl)bis(3-(trifluoromethyl)phenyl)phosphine oxide
• CAS No.: 1443418-91-4
• Molecular Formula: C₂₅H₁₆F₆NOP
• Molecular Weight: 491.372
• Mol file: 1443418-91-4.mol

Synonyms:(2-(pyridin-2-yl)phenyl)bis(3-(trifluoromethyl)phenyl)phosphine oxide

Chemical Property of (2-(pyridin-2-yl)phenyl)bis(3-(trifluoromethyl)phenyl)phosphine oxide

Chemical Property:

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Technology Process of (2-(pyridin-2-yl)phenyl)bis(3-(trifluoromethyl)phenyl)phosphine oxide

There total 1 articles about (2-(pyridin-2-yl)phenyl)bis(3-(trifluoromethyl)phenyl)phosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

2-phenylpyridine (1008-89-5) + bis(α,α,α-trifluoro-3-tolyl)phosphine oxide (15929-44-9) → (2-(pyridin-2-yl)phenyl)bis(3-(trifluoromethyl)phenyl)phosphine oxide (1443418-91-4)

Guidance literature:

2-phenylpyridine; With silver(I) acetate; sodium acetate; palladium diacetate; In tert-Amyl alcohol; at 120 ℃; for 0.166667h; Sealed tube;

bis(α,α,α-trifluoro-3-tolyl)phosphine oxide; With p-benzoquinone; In tert-Amyl alcohol; at 120 ℃; for 13h; Sealed tube;

DOI:10.1021/ja404526x

upstream raw materials:

2-phenylpyridine

bis(α,α,α-trifluoro-3-tolyl)phosphine oxide