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gamma-Linolenic acid

Base Information Edit
  • Chemical Name:gamma-Linolenic acid
  • CAS No.:506-26-3
  • Molecular Formula:C18H30 O2
  • Molecular Weight:278.435
  • Hs Code.:2916190090
  • Mol file:506-26-3.mol
gamma-Linolenic acid

Synonyms:6,9,12-Octadecatrienoicacid, (Z,Z,Z)-; g-Linolenicacid (6CI,7CI,8CI); (Z,Z,Z)-6,9,12-Octatrienoic acid; 6(Z),9(Z),12(Z)-Octadecatrienoicacid; 6,9,12-all-cis-Octadecatrienoic acid; 6-cis,9-cis,12-cis-Octadecatrienoicacid; Gamma-linolenic acid; Gamolenic acid; all-cis-6,9,12-Octadecatrienoicacid; cis,cis,cis-6,9,12-Octadecatrienoic acid; cis-6,cis-9,cis-12-Octadecatrienoicacid

Suppliers and Price of gamma-Linolenic acid
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • γ-Linolenic Acid
  • 500mg
  • $ 460.00
  • TRC
  • γ-Linolenic acid
  • 50mg
  • $ 75.00
  • TCI Chemical
  • γ-Linolenic Acid >98.0%(GC)(T)
  • 1g
  • $ 422.00
  • TCI Chemical
  • γ-Linolenic Acid >98.0%(GC)(T)
  • 100mg
  • $ 85.00
  • Sigma-Aldrich
  • γ-Linolenic acid ≥99%, liquid
  • 10mg
  • $ 55.20
  • Sigma-Aldrich
  • γ-Linolenic acid analyticalstandard
  • 100 mg
  • $ 175.00
  • Sigma-Aldrich
  • γ-Linolenic acid analytical standard
  • 100mg-f
  • $ 170.00
  • Sigma-Aldrich
  • γ-Linolenic acid ≥99%, liquid
  • 100mg
  • $ 113.00
  • Sigma-Aldrich
  • γ-Linolenic acid analyticalstandard
  • 500 mg
  • $ 483.00
  • Sigma-Aldrich
  • γ-Linolenic acid analytical standard
  • 500mg-f
  • $ 468.00
Total 84 raw suppliers
Chemical Property of gamma-Linolenic acid Edit
Chemical Property:
  • Vapor Pressure:8.26E-07mmHg at 25°C 
  • Melting Point:-12~-11℃ 
  • Refractive Index:n20/D 1.471 
  • Boiling Point:379.5°Cat760mmHg 
  • PKA:4.74±0.10(Predicted) 
  • Flash Point:276.4°C 
  • PSA:37.30000 
  • Density:0.924g/cm3 
  • LogP:5.66050 
  • Storage Temp.:−20°C 
  • Solubility.:Chloroform (Sparingly), DMSO (Slightly), Methanol (Slightly) 
Purity/Quality:

99%, *data from raw suppliers

γ-Linolenic Acid *data from reagent suppliers

Safty Information:
  • Pictogram(s): Xi 
  • Hazard Codes:Xi 
  • Statements: 36/37/38 
  • Safety Statements: 26-36 
MSDS Files:
Useful:
  • Description γ-Linolenic acid (gamma-linolenic acid or GLA, INN and USAN gamolenic acid) is a fatty acid found primarily in vegetable oils. It is sold as a dietary supplement for treating problems with inflammation and auto-immune diseases, although its efficacy is disputed. γ-Linolenic acid (GLA) is an ω-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak LTB4 receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki of 1 μM. GLA produces 53% inhibition at a 1 mg/kg dose in an in vivo model of LTB4-induced bronchoconstriction.
  • Uses γ-Linolenic Acid is a fatty acid found mainly in vegetable oil. Studies suggest that γ-Linolenic Acid may have immune regulating and anti-inflammatory effects. γ-Linolenic Acid has also been used in the treatment of atopic eczeme although its efficacy is γ-linolenic acid has been used as an analytical standard in gas chromatography. It may be used in nutritional studies regarding weight regain and as a possible tumor suppression agent. γ-linolenic acid is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids.
Technology Process of gamma-Linolenic acid

There total 21 articles about gamma-Linolenic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With lithium hydroxide; water; In tetrahydrofuran; 1.) 0 deg C, 30 min, 2.) r.t., 12 h;
DOI:10.1055/s-1998-2104
Guidance literature:
With water; sodium hydroxide; In ethanol; at 30 - 50 ℃; for 0.5h; Inert atmosphere;
Guidance literature:
With quinoline; Lindlar's catalyst; ethanol; Hydrogenation;
Refernces Edit
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