N,N'-Bis-((1R,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-2,2-dimethyl-malonamide

Base Information

Chemical Name:N,N'-Bis-((1R,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-2,2-dimethyl-malonamide
CAS No.:183866-65-1
Molecular Formula:C₂₃H₃₀N₂O₄
Molecular Weight:398.502
Hs Code.:

Synonyms:N,N'-Bis-((1R,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-2,2-dimethyl-malonamide

Suppliers and Price of N,N'-Bis-((1R,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-2,2-dimethyl-malonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N,N'-Bis-((1R,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-2,2-dimethyl-malonamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N,N'-Bis-((1R,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-2,2-dimethyl-malonamide

There total 1 articles about N,N'-Bis-((1R,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-2,2-dimethyl-malonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 40626-29-7
Acutrim

: 5659-93-8
2,2-Dimethylmalonyl chloride

: 183866-65-1
N,N'-Bis-((1R,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-2,2-dimethyl-malonamide

Guidance literature:: With triethylamine; Yield given. Multistep reaction; 1.) CH₂Cl₂, 1 h, 2.) CH₂Cl₂, RT, overnight;
DOI:10.1016/0040-4020(96)00817-4

Reference yield: 65.0%

: 183866-65-1
N,N'-Bis-((1R,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-2,2-dimethyl-malonamide

: 2,2-bis[2-(4(R)-methyl-5(S)-phenyl-1,3-oxazolinyl)]propane

Guidance literature:: With dibutyltin chloride; In xylene; for 288h; Heating;
DOI:10.1016/0040-4020(96)00817-4

Reference yield:

: 183866-65-1
N,N'-Bis-((1R,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-2,2-dimethyl-malonamide

: 2,2-bis[2-(4(R)-methyl-5(R)-phenyl-1,3-oxazolinyl)]propane

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂ / 4 h / Ambient temperature

2: aq. NaOH / ethanol / 3 h / Heating

With sodium hydroxide; triethylamine; In ethanol; dichloromethane;
DOI:10.1016/0040-4020(96)00817-4