2'-O-(t-butyldimethylsilyl)-3'-deoxy-5'C,5'-O-didehydro-N₄-(4-methoxytrityl)cytidine

Base Information

• Chemical Name: 2'-O-(t-butyldimethylsilyl)-3'-deoxy-5'C,5'-O-didehydro-N₄-(4-methoxytrityl)cytidine
• CAS No.: 1246254-64-7
• Molecular Formula: C₃₅H₄₁N₃O₅Si
• Molecular Weight: 611.813

Synonyms:2'-O-(t-butyldimethylsilyl)-3'-deoxy-5'C,5'-O-didehydro-N₄-(4-methoxytrityl)cytidine

Chemical Property of 2'-O-(t-butyldimethylsilyl)-3'-deoxy-5'C,5'-O-didehydro-N₄-(4-methoxytrityl)cytidine

Chemical Property:

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Technology Process of 2'-O-(t-butyldimethylsilyl)-3'-deoxy-5'C,5'-O-didehydro-N₄-(4-methoxytrityl)cytidine

There total 1 articles about 2'-O-(t-butyldimethylsilyl)-3'-deoxy-5'C,5'-O-didehydro-N₄-(4-methoxytrityl)cytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.9%

2'-O-(t-butyldimethylsilyl)-3'-deoxy-N4-(4-methoxytrityl)cytidine (1246254-63-6) → 2'-O-(t-butyldimethylsilyl)-3'-deoxy-5'C,5'-O-didehydro-N4-(4-methoxytrityl)cytidine (1246254-64-7)

Guidance literature:

With pyridine; Dess-Martin periodane; In dichloromethane; at 20 ℃; Inert atmosphere; Cooling with ice;

upstream raw materials:

2'-O-(t-butyldimethylsilyl)-3'-deoxy-N₄-(4-methoxytrityl)cytidine

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