(-)-alpha-Copaene

Base Information

Chemical Name:(-)-alpha-Copaene
CAS No.:3856-25-5
Molecular Formula:C15H24
Molecular Weight:204.356
Hs Code.:
European Community (EC) Number:223-364-4
UNII:0V56HXQ8N5
Metabolomics Workbench ID:53523
Wikidata:Q27237288
Wikipedia:Copaene
Mol file:3856-25-5.mol

Synonyms:alpha-copaene

Suppliers and Price of (-)-alpha-Copaene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
α-Copaene
10mg
$ 1100.00

Medical Isotopes, Inc.
α-Copaene
1 mg
$ 290.00

Cayman Chemical
α-Copaene ≥98%
1mg
$ 169.00

Cayman Chemical
α-Copaene ≥98%
500μg
$ 95.00

American Custom Chemicals Corporation
(-)-ALPHA-COPAENE 70.30%
1G
$ 5775.00

American Custom Chemicals Corporation
(-)-ALPHA-COPAENE 70.30%
100MG
$ 3097.50

American Custom Chemicals Corporation
(-)-ALPHA-COPAENE 70.30%
10MG
$ 945.00

American Custom Chemicals Corporation
(-)-ALPHA-COPAENE 70.30%
5MG
$ 764.50

Total 37 raw suppliers

Chemical Property of (-)-alpha-Copaene

Chemical Property:

Vapor Pressure:0.038mmHg at 25°C
Melting Point:74 °C
Refractive Index:n20/D 1.490
Boiling Point:248.5°Cat760mmHg
Flash Point:105.1°C
PSA：0.00000
Density:0.939g/cm³
LogP:4.27090
Storage Temp.:−20°C
Solubility.:Chloroform (Sparingly), Methanol (Slightly)
XLogP3:4.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:1
Exact Mass:204.187800766
Heavy Atom Count:15
Complexity:312

Purity/Quality:

99% ^*data from raw suppliers

α-Copaene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CCC2C3C1C2(CCC3C(C)C)C
Isomeric SMILES:CC1=CC[C@H]2[C@H]3[C@@H]1[C@@]2(CC[C@H]3C(C)C)C
Description α-Copaene is a sesquiterpene found in a variety of plants, including Cannabis, that has antiproliferative and antioxidant properties. It inhibits proliferation of primary rat neurons and N2a rat neuroblastoma cells in a concentration-dependent manner and cultured human lymphocytes when used at concentrations greater than 100 mg/L. α-Copaene (25 mg/L) increases total antioxidant capacity in primary rat neurons and N2a neuroblastoma cells, as well as cultured human lymphocytes, when used at concentrations of 50 and 100 mg/L.
Uses α-Copaene is a tricyclic?sesquiterpenes?and can be extracted from the oil of S. aethiopis. It also exhibit anti-plasmodial activity against?P. falciparum in culture.

Technology Process of (-)-alpha-Copaene

There total 16 articles about (-)-alpha-Copaene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 18252-44-3,20479-06-5,28129-91-1,29484-26-2,41530-63-6,41530-64-7,70115-82-1,147515-11-5
(+/-)-β-copaene

: 947-59-1,3856-25-5,13567-62-9,14912-44-8,15493-66-0,15917-91-6,138874-68-7
α-copaene

Guidance literature:: With hydrogen iodide; In benzene; for 0.75h;

Reference yield: 2.5%

: 105453-16-5
germacrene D

: 483-76-1,13061-82-0,16729-01-4,20085-20-5,60305-17-1,73365-79-4
(±)-δ-cadinene

: 947-59-1,3856-25-5,13567-62-9,14912-44-8,15493-66-0,15917-91-6,138874-68-7
α-copaene

: 39029-41-9
γ-cadinene

: 30021-74-0
γ-muurolene

Guidance literature:: With silica gel; In hexane; for 48h; Further byproducts given;
DOI:10.1016/S0031-9422(00)00266-1

Reference yield:

: 40716-68-5
(2-cis,6-trans)-farnesyl diphosphate

: 1461-03-6
β-himachalene

: 3853-83-6
α-himachalene

: 1891-45-8
2-himachalen-7-ol

: 947-59-1,3856-25-5,13567-62-9,14912-44-8,15493-66-0,15917-91-6,138874-68-7
α-ylangene

: 53111-25-4
γ-cis-himachalane

: humula-4,9-dien-8-ol

: isobicyclogermacrene

: γ-humulene

: δ–amorphene

: α-Amorphene

Guidance literature:: With Medicago truncatula multiproduct sesquiterpene synthase; In pentane; at 30 ℃; for 1.5h; pH=7.5; stereospecific reaction; Enzymatic reaction;
DOI:10.1021/acs.joc.6b02696