7-(4-(5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl)benzyloxy)-3-(2-pyridyl)coumarin

Base Information

Chemical Name:7-(4-(5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl)benzyloxy)-3-(2-pyridyl)coumarin
CAS No.:1353055-79-4
Molecular Formula:C₃₃H₂₇N₃O₄
Molecular Weight:529.595
Hs Code.:

Synonyms:7-(4-(5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl)benzyloxy)-3-(2-pyridyl)coumarin

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Chemical Property of 7-(4-(5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl)benzyloxy)-3-(2-pyridyl)coumarin

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Technology Process of 7-(4-(5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl)benzyloxy)-3-(2-pyridyl)coumarin

There total 4 articles about 7-(4-(5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl)benzyloxy)-3-(2-pyridyl)coumarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.5%

: 1148-28-3
7-hydroxy-3-(2-pyridinyl)-2H-1-benzopyran-2-one

: 253878-40-9
2-[4-(bromomethyl)phenyl]-5-(4-tert-butylphenyl)-1,3,4-oxadiazole

: 1353055-79-4
7-(4-(5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl)benzyloxy)-3-(2-pyridyl)coumarin

Guidance literature:: With potassium carbonate; In butanone; at 70 ℃; for 72h; Inert atmosphere;
DOI:10.1007/s11164-011-0339-2

Reference yield:

: 1001226-97-6
C₁₄H₁₀N₂O₂

: 1353055-79-4
7-(4-(5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl)benzyloxy)-3-(2-pyridyl)coumarin

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid; water / ethanol / 8 h / Reflux

2: potassium carbonate / butanone / 72 h / 70 °C / Inert atmosphere

With sulfuric acid; water; potassium carbonate; In ethanol; butanone;
DOI:10.1007/s11164-011-0339-2

Reference yield:

: 2739-97-1
pyridine-2-acetonitrile

: 1353055-79-4
7-(4-(5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl)benzyloxy)-3-(2-pyridyl)coumarin

Guidance literature:: Multi-step reaction with 3 steps

1: piperidine / ethanol / 12 h / 20 °C

2: sulfuric acid; water / ethanol / 8 h / Reflux

3: potassium carbonate / butanone / 72 h / 70 °C / Inert atmosphere

With piperidine; sulfuric acid; water; potassium carbonate; In ethanol; butanone;
DOI:10.1007/s11164-011-0339-2