6-N-bis-t-butoxycarbonyl-2',3'-O-isopropylidene-5'-N-(N-[4''-(2'''-[methoxycarbonyl]phenyl)pent-4-enoyl]sulfamoyl)aminodeoxyadenosine

Base Information

Chemical Name:6-N-bis-t-butoxycarbonyl-2',3'-O-isopropylidene-5'-N-(N-[4''-(2'''-[methoxycarbonyl]phenyl)pent-4-enoyl]sulfamoyl)aminodeoxyadenosine
CAS No.:1094678-02-0
Molecular Formula:C₃₁H₃₉N₇O₁₀S
Molecular Weight:701.758
Hs Code.:

Synonyms:6-N-bis-t-butoxycarbonyl-2',3'-O-isopropylidene-5'-N-(N-[4''-(2'''-[methoxycarbonyl]phenyl)pent-4-enoyl]sulfamoyl)aminodeoxyadenosine

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Chemical Property of 6-N-bis-t-butoxycarbonyl-2',3'-O-isopropylidene-5'-N-(N-[4''-(2'''-[methoxycarbonyl]phenyl)pent-4-enoyl]sulfamoyl)aminodeoxyadenosine

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Technology Process of 6-N-bis-t-butoxycarbonyl-2',3'-O-isopropylidene-5'-N-(N-[4''-(2'''-[methoxycarbonyl]phenyl)pent-4-enoyl]sulfamoyl)aminodeoxyadenosine

There total 1 articles about 6-N-bis-t-butoxycarbonyl-2',3'-O-isopropylidene-5'-N-(N-[4''-(2'''-[methoxycarbonyl]phenyl)pent-4-enoyl]sulfamoyl)aminodeoxyadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 873556-46-8
tert-butyl 9-(((3aR,4R,6R,6aR)-2,2-dimethyl-6-((sulfamoylamino)methyl)tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-9H-purin-6-yl)carbamate

: 1094677-78-7
4-(2'-[methoxycarbonyl]phenyl)pent-4-enoic acid

: 1094678-02-0
6-N-bis-t-butoxycarbonyl-2',3'-O-isopropylidene-5'-N-(N-[4''-(2'''-[methoxycarbonyl]phenyl)pent-4-enoyl]sulfamoyl)aminodeoxyadenosine

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1016/j.bmcl.2008.07.130