2-Carbamoyl-2-fluoro-3-methylpentanoic acid

Base Information

Chemical Name:2-Carbamoyl-2-fluoro-3-methylpentanoic acid
CAS No.:18283-39-1
Molecular Formula:C₇H₁₂FNO₃
Molecular Weight:177.176
Hs Code.:
NSC Number:87257
DSSTox Substance ID:DTXSID20293119
Mol file:18283-39-1.mol

Synonyms:18283-39-1;2-carbamoyl-2-fluoro-3-methylpentanoic acid;NSC87257;NCIOpen2_001110;DTXSID20293119;NSC-87257

Suppliers and Price of 2-Carbamoyl-2-fluoro-3-methylpentanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-Carbamoyl-2-fluoro-3-methylpentanoic acid

Chemical Property:

Vapor Pressure:4.89E-06mmHg at 25°C
Boiling Point:356.3°Cat760mmHg
Flash Point:169.3°C
Density:1.218g/cm³
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:177.08012141
Heavy Atom Count:12
Complexity:207

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C)C(C(=O)N)(C(=O)O)F

Technology Process of 2-Carbamoyl-2-fluoro-3-methylpentanoic acid

There total 2 articles about 2-Carbamoyl-2-fluoro-3-methylpentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 18283-27-7
2-Cyano-2-fluoro-3-methyl-pentanoic acid ethyl ester

: 18283-39-1
2-Carbamoyl-2-fluoro-3-methyl-pentanoic acid

Guidance literature:: With sodium hydroxide;
DOI:10.1021/jm00316a008

Reference yield:

: 7309-45-7
ethyl 2-cyano-3-methylvalerate

: 18283-39-1
2-Carbamoyl-2-fluoro-3-methyl-pentanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: (i) Na, toluene, (ii) ClO₃F

2: aq. NaOH

With sodium hydroxide;
DOI:10.1021/jm00316a008