(R)-2-[3-((R)-1,3-Bis-benzyloxycarbonyl-propyl)-ureido]-pentanedioic acid dibenzyl ester

Base Information

• Chemical Name: (R)-2-[3-((R)-1,3-Bis-benzyloxycarbonyl-propyl)-ureido]-pentanedioic acid dibenzyl ester
• CAS No.: 302941-56-6
• Molecular Formula: C₃₉H₄₀N₂O₉
• Molecular Weight: 680.755
• Mol file: 302941-56-6.mol

Synonyms:(R)-2-[3-((R)-1,3-Bis-benzyloxycarbonyl-propyl)-ureido]-pentanedioic acid dibenzyl ester

Chemical Property of (R)-2-[3-((R)-1,3-Bis-benzyloxycarbonyl-propyl)-ureido]-pentanedioic acid dibenzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-2-[3-((R)-1,3-Bis-benzyloxycarbonyl-propyl)-ureido]-pentanedioic acid dibenzyl ester

There total 2 articles about (R)-2-[3-((R)-1,3-Bis-benzyloxycarbonyl-propyl)-ureido]-pentanedioic acid dibenzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-glutamic acid dibenzyl ester (47376-46-5) + (R)-2-Isocyanato-pentanedioic acid dibenzyl ester → (R)-2-[3-((R)-1,3-Bis-benzyloxycarbonyl-propyl)-ureido]-pentanedioic acid dibenzyl ester (302941-56-6)

Guidance literature:

With triethylamine; In dichloromethane; at -78 - 20 ℃;

DOI:10.1021/jm000406m

Reference yield:

D-glutamic acid dibenzyl ester (47376-46-5) → (R)-2-[3-((R)-1,3-Bis-benzyloxycarbonyl-propyl)-ureido]-pentanedioic acid dibenzyl ester (302941-56-6)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂ / -78 °C

2: Et₃N / CH₂Cl₂ / -78 - 20 °C

With triethylamine; In dichloromethane;

DOI:10.1021/jm000406m

upstream raw materials:

D-glutamic acid dibenzyl ester