(3Z,5E)-3-Methyl-2-oxo-6-phenyl-hexa-3,5-dienoic acid methyl ester

Base Information

• Chemical Name: (3Z,5E)-3-Methyl-2-oxo-6-phenyl-hexa-3,5-dienoic acid methyl ester
• CAS No.: 81429-02-9
• Molecular Formula: C₁₄H₁₄O₃
• Molecular Weight: 230.263
• Mol file: 81429-02-9.mol

Synonyms:(3Z,5E)-3-Methyl-2-oxo-6-phenyl-hexa-3,5-dienoic acid methyl ester

Chemical Property of (3Z,5E)-3-Methyl-2-oxo-6-phenyl-hexa-3,5-dienoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3Z,5E)-3-Methyl-2-oxo-6-phenyl-hexa-3,5-dienoic acid methyl ester

There total 5 articles about (3Z,5E)-3-Methyl-2-oxo-6-phenyl-hexa-3,5-dienoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3Z,5E)-2-Hydroxy-3-methyl-6-phenyl-hexa-3,5-dienoic acid methyl ester (111193-95-4) → (3Z,5E)-3-Methyl-2-oxo-6-phenyl-hexa-3,5-dienoic acid methyl ester (81429-02-9)

Guidance literature:

With manganese(IV) oxide; In dichloromethane; for 0.166667h; Ambient temperature;

DOI:10.1016/S0040-4039(00)95760-5

Reference yield:

(2Z,4E)-2-methyl-5-phenylpenta-2,4-dien-1-ol (54355-96-3) → (3Z,5E)-3-Methyl-2-oxo-6-phenyl-hexa-3,5-dienoic acid methyl ester (81429-02-9)

Guidance literature:

Multi-step reaction with 3 steps

1: MnO₂ / CH₂Cl₂ / 3 h / Ambient temperature

2: 2.)HgCl₂, HgO / 1.)THF, -70 deg C; 2.)MeOH; H₂O, room temp., 15 min

3: MnO₂ / CH₂Cl₂ / 0.17 h / Ambient temperature

With manganese(IV) oxide; mercury dichloride; mercury(II) oxide; In dichloromethane;

DOI:10.1016/S0040-4039(00)95760-5

Reference yield:

(2Z,4E)-2-Methyl-5-phenyl-penta-2,4-dienal (111193-92-1) → (3Z,5E)-3-Methyl-2-oxo-6-phenyl-hexa-3,5-dienoic acid methyl ester (81429-02-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 2.)HgCl₂, HgO / 1.)THF, -70 deg C; 2.)MeOH; H₂O, room temp., 15 min

2: MnO₂ / CH₂Cl₂ / 0.17 h / Ambient temperature

With manganese(IV) oxide; mercury dichloride; mercury(II) oxide; In dichloromethane;

DOI:10.1016/S0040-4039(00)95760-5

upstream raw materials:

(3Z,5E)-2-Hydroxy-3-methyl-6-phenyl-hexa-3,5-dienoic acid methyl ester

(2Z,4E)-2-methyl-5-phenylpenta-2,4-dien-1-ol

(2Z,4E)-2-Methyl-5-phenyl-penta-2,4-dienal

ethyl (2Z,4E)-2-methyl-5-phenylpenta-2,4-dienoate

Downstream raw materials:

methyl (2E,3Z,5E)-2-(methoxymethylene)-3-methyl-6-phenylhexa-3,5-dienoate

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