(1S,3aR,7aS)-4,4-Dimethyl-6-oxo-hexahydro-pyrano[3,4-c]pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-methyl ester

Base Information

Chemical Name:(1S,3aR,7aS)-4,4-Dimethyl-6-oxo-hexahydro-pyrano[3,4-c]pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-methyl ester
CAS No.:115890-54-5
Molecular Formula:C₁₉H₂₃NO₆
Molecular Weight:361.395
Hs Code.:

Synonyms:(1S,3aR,7aS)-4,4-Dimethyl-6-oxo-hexahydro-pyrano[3,4-c]pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-methyl ester

Suppliers and Price of (1S,3aR,7aS)-4,4-Dimethyl-6-oxo-hexahydro-pyrano[3,4-c]pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,3aR,7aS)-4,4-Dimethyl-6-oxo-hexahydro-pyrano[3,4-c]pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,3aR,7aS)-4,4-Dimethyl-6-oxo-hexahydro-pyrano[3,4-c]pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-methyl ester

There total 9 articles about (1S,3aR,7aS)-4,4-Dimethyl-6-oxo-hexahydro-pyrano[3,4-c]pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 115890-38-5
((R)-2-Benzyloxy-1-formyl-ethyl)-(3-methyl-but-2-enyl)-carbamic acid benzyl ester

: 115890-54-5
(1S,3aR,7aS)-4,4-Dimethyl-6-oxo-hexahydro-pyrano[3,4-c]pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-methyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 4.24 g / ethylenediammonium diacetate / propan-2-ol / 16 h / Ambient temperature

2: 2.27 g / H₂O / dioxane / 15 h / Heating

3: 41 percent / BBr₃ / CH₂Cl₂ / 1.) -40 deg C to 0 deg C, 1 h, 2.) 0 deg C, 30 min

4: 84 percent / 8 N Jones reagent / acetone / 1.) 0 deg C, 3 h, 2.) r.t., 10 h

5: 90 mg / methanol; diethyl ether / 0 °C

With jones reagent; water; boron tribromide; ethylenediamine diacetic acid; In 1,4-dioxane; methanol; diethyl ether; dichloromethane; isopropyl alcohol; acetone;
DOI:10.1021/ja00227a029

Reference yield:

: (2R,3RS)-2-<(benzyloxycarbonyl)prenylamino>-1-(benzyloxy)-3,4-butandiol

: 115890-54-5
(1S,3aR,7aS)-4,4-Dimethyl-6-oxo-hexahydro-pyrano[3,4-c]pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-methyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 3.27 g / NaIO₄ / methanol; H₂O / 2 h / 0 °C

2: 4.24 g / ethylenediammonium diacetate / propan-2-ol / 16 h / Ambient temperature

3: 2.27 g / H₂O / dioxane / 15 h / Heating

4: 41 percent / BBr₃ / CH₂Cl₂ / 1.) -40 deg C to 0 deg C, 1 h, 2.) 0 deg C, 30 min

5: 84 percent / 8 N Jones reagent / acetone / 1.) 0 deg C, 3 h, 2.) r.t., 10 h

6: 90 mg / methanol; diethyl ether / 0 °C

With sodium periodate; jones reagent; water; boron tribromide; ethylenediamine diacetic acid; In 1,4-dioxane; methanol; diethyl ether; dichloromethane; water; isopropyl alcohol; acetone;
DOI:10.1021/ja00227a029

Reference yield:

: (2S,3S,4R)-<1-(benzyloxycarbonyl)-2-<(benzyloxy)methyl>-4-(1-hydroxy-1-methylethyl)>-3-pyrrolidineacetic acid lactone

: 115890-54-5
(1S,3aR,7aS)-4,4-Dimethyl-6-oxo-hexahydro-pyrano[3,4-c]pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 41 percent / BBr₃ / CH₂Cl₂ / 1.) -40 deg C to 0 deg C, 1 h, 2.) 0 deg C, 30 min

2: 84 percent / 8 N Jones reagent / acetone / 1.) 0 deg C, 3 h, 2.) r.t., 10 h

3: 90 mg / methanol; diethyl ether / 0 °C

With jones reagent; boron tribromide; In methanol; diethyl ether; dichloromethane; acetone;
DOI:10.1021/ja00227a029