(2R,3S)-2-tert-butoxycarbonylamino-5-(2-chloro-4,5-dimethoxy-phenoxy)-3-hydroxypentanoic acid methyl ester

Base Information

Chemical Name:(2R,3S)-2-tert-butoxycarbonylamino-5-(2-chloro-4,5-dimethoxy-phenoxy)-3-hydroxypentanoic acid methyl ester
CAS No.:1052273-26-3
Molecular Formula:C₁₉H₂₈ClNO₈
Molecular Weight:433.886
Hs Code.:

Synonyms:(2R,3S)-2-tert-butoxycarbonylamino-5-(2-chloro-4,5-dimethoxy-phenoxy)-3-hydroxypentanoic acid methyl ester

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Chemical Property of (2R,3S)-2-tert-butoxycarbonylamino-5-(2-chloro-4,5-dimethoxy-phenoxy)-3-hydroxypentanoic acid methyl ester

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Technology Process of (2R,3S)-2-tert-butoxycarbonylamino-5-(2-chloro-4,5-dimethoxy-phenoxy)-3-hydroxypentanoic acid methyl ester

There total 1 articles about (2R,3S)-2-tert-butoxycarbonylamino-5-(2-chloro-4,5-dimethoxy-phenoxy)-3-hydroxypentanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 4248-19-5
tert-butyl carbazate

: 1052273-23-0
(2E)-5-(3,4-dimethoxy-phenoxy)-pent-2-enoic acid, methyl ester

: 1052273-26-3
(2R,3S)-2-tert-butoxycarbonylamino-5-(2-chloro-4,5-dimethoxy-phenoxy)-3-hydroxypentanoic acid methyl ester

: 3-tert-Butoxycarbonylamino-5-(2-chloro-4,5-dimethoxy-phenoxy)-2-hydroxypentanoic acid methyl ester

Guidance literature:: With potassium osmate(VI) dihydrate; sodium hydroxide; 1,3-dichloro-5,5-dimethylhydantoin; hydroquinine (anthraquinone-1,4-diyl) diether; In propan-1-ol; water; at 20 ℃; for 19h; optical yield given as %ee; enantioselective reaction;
DOI:10.1039/b803310b