2-fluoro-5-methoxyphenylalanine hydrochloride

Base Information

Chemical Name:2-fluoro-5-methoxyphenylalanine hydrochloride
CAS No.:1021301-31-4
Molecular Formula:C₁₀H₁₂FNO₃*ClH
Molecular Weight:249.67
Hs Code.:

Synonyms:2-fluoro-5-methoxyphenylalanine hydrochloride

Suppliers and Price of 2-fluoro-5-methoxyphenylalanine hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-fluoro-5-methoxyphenylalanine hydrochloride

Chemical Property:

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Technology Process of 2-fluoro-5-methoxyphenylalanine hydrochloride

There total 3 articles about 2-fluoro-5-methoxyphenylalanine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 845552-59-2
diethyl (2-fluoro-5-methoxybenzyl)(formylamino)malonate

: 1021301-37-0
2-fluoro-5-hydroxyphenylalanine hydrochloride

: 1021301-31-4
2-fluoro-5-methoxyphenylalanine hydrochloride

Guidance literature:: With hydrogenchloride; In water; acetic acid; at 100 - 120 ℃; for 24h;

Reference yield:

: 845552-60-5
C₉H₁₁FO₄S

: 1021301-37-0
2-fluoro-5-hydroxyphenylalanine hydrochloride

: 1021301-31-4
2-fluoro-5-methoxyphenylalanine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / DMF (N,N-dimethyl-formamide) / 0.17 h / 0 °C

1.2: 16.5 h / 0 - 20 °C

2.1: hydrogenchloride / water; acetic acid / 24 h / 100 - 120 °C

With hydrogenchloride; sodium hydride; In DMF (N,N-dimethyl-formamide); water; acetic acid;

Reference yield:

: 161643-29-4
(2-fluoro-5-methoxyphenyl)methanol

: 1021301-37-0
2-fluoro-5-hydroxyphenylalanine hydrochloride

: 1021301-31-4
2-fluoro-5-methoxyphenylalanine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / dichloromethane / 1 h / 0 °C

2.1: sodium hydride / DMF (N,N-dimethyl-formamide) / 0.17 h / 0 °C

2.2: 16.5 h / 0 - 20 °C

3.1: hydrogenchloride / water; acetic acid / 24 h / 100 - 120 °C

With hydrogenchloride; sodium hydride; triethylamine; In DMF (N,N-dimethyl-formamide); dichloromethane; water; acetic acid;