Diethyl p-acetoxyphenylphosphonate

Base Information

Chemical Name:Diethyl p-acetoxyphenylphosphonate
CAS No.:25944-72-3
Molecular Formula:C₁₂H₁₇O₅P
Molecular Weight:272.238
Hs Code.:
DSSTox Substance ID:DTXSID901266418

Synonyms:diethyl p-acetoxyphenylphosphonate;SCHEMBL12012734;DTXSID901266418;25944-72-3;Diethyl P-[4-(acetyloxy)phenyl]phosphonate

Suppliers and Price of Diethyl p-acetoxyphenylphosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Diethyl p-acetoxyphenylphosphonate

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:272.08136064
Heavy Atom Count:18
Complexity:300

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOP(=O)(C1=CC=C(C=C1)OC(=O)C)OCC

Technology Process of Diethyl p-acetoxyphenylphosphonate

There total 4 articles about Diethyl p-acetoxyphenylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1927-95-3
4-bromophenyl acetate

: 122-52-1
triethyl phosphite

: 25944-72-3
diethyl p-acetoxyphenylphosphonate

Guidance literature:: With nickel dichloride; at 180 ℃; for 0.5h;

Reference yield: 58.0%

: 1927-95-3
4-bromophenyl acetate

: 762-04-9
phosphonic acid diethyl ester

: 25944-72-3
diethyl p-acetoxyphenylphosphonate

Guidance literature:: With triethylsilane; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In toluene; at 90 ℃; for 22h;

Reference yield:

: 106-41-2
4-bromo-phenol

: 25944-72-3
diethyl p-acetoxyphenylphosphonate

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / H₂SO₄ / 3 h / Heating

2: 29.66 percent / nickel(II) chloride / 2 h / 170 °C

With sulfuric acid; nickel dichloride;
DOI:10.1023/B:RUGC.0000018643.28412.96