2-({[4-(4-cyclopropylbuta-1,3-diyn-1-yl)phenyl]carbonyl}(methyl)amino)-N-hydroxy-N'-methylpropanediamide

Base Information

Chemical Name:2-({[4-(4-cyclopropylbuta-1,3-diyn-1-yl)phenyl]carbonyl}(methyl)amino)-N-hydroxy-N'-methylpropanediamide
CAS No.:1344698-60-7
Molecular Formula:C₁₉H₁₉N₃O₄
Molecular Weight:353.378
Hs Code.:

Synonyms:2-({[4-(4-cyclopropylbuta-1,3-diyn-1-yl)phenyl]carbonyl}(methyl)amino)-N-hydroxy-N'-methylpropanediamide

Suppliers and Price of 2-({[4-(4-cyclopropylbuta-1,3-diyn-1-yl)phenyl]carbonyl}(methyl)amino)-N-hydroxy-N'-methylpropanediamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-({[4-(4-cyclopropylbuta-1,3-diyn-1-yl)phenyl]carbonyl}(methyl)amino)-N-hydroxy-N'-methylpropanediamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-({[4-(4-cyclopropylbuta-1,3-diyn-1-yl)phenyl]carbonyl}(methyl)amino)-N-hydroxy-N'-methylpropanediamide

There total 7 articles about 2-({[4-(4-cyclopropylbuta-1,3-diyn-1-yl)phenyl]carbonyl}(methyl)amino)-N-hydroxy-N'-methylpropanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1344700-32-8
1-(4-cyclopropylbuta-1,3-diyn-1-yl)-4-{[1-methoxy-3-(methylamino)-1,3-dioxopropan-2-yl](methyl)carbamoyl}benzene

: 1344698-60-7
2-({[4-(4-cyclopropylbuta-1,3-diyn-1-yl)phenyl]carbonyl}(methyl)amino)-N-hydroxy-N'-methylpropanediamide

Guidance literature:: With water; hydroxylamine; In methanol; for 3.5h; Cooling with ice;

Reference yield:

: 1344700-30-6
4-(4-cyclopropylbuta-1,3-diyn-1-yl)benzoic acid methyl ester

: 1344698-60-7
2-({[4-(4-cyclopropylbuta-1,3-diyn-1-yl)phenyl]carbonyl}(methyl)amino)-N-hydroxy-N'-methylpropanediamide

Guidance literature:: Multi-step reaction with 3 steps

1: water; sodium hydroxide / methanol; 1,4-dioxane / 2.5 h / 20 °C

2: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2.5 h / 2 °C

3: hydroxylamine; water / methanol / 3.5 h / Cooling with ice

With water; hydroxylamine; N-ethyl-N,N-diisopropylamine; HATU; sodium hydroxide; In 1,4-dioxane; methanol; N,N-dimethyl-formamide;

Reference yield:

: 1093193-97-5
4-(4-cyclopropylbuta-1,3-diyn-1-yl)benzoic acid

: 1344698-60-7
2-({[4-(4-cyclopropylbuta-1,3-diyn-1-yl)phenyl]carbonyl}(methyl)amino)-N-hydroxy-N'-methylpropanediamide

Guidance literature:: Multi-step reaction with 2 steps

1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2.5 h / 2 °C

2: hydroxylamine; water / methanol / 3.5 h / Cooling with ice

With water; hydroxylamine; N-ethyl-N,N-diisopropylamine; HATU; In methanol; N,N-dimethyl-formamide;