1,3-bis-(3,4,5-trimethoxybenzyl)benzimidazolium chloride

Base Information

• Chemical Name: 1,3-bis-(3,4,5-trimethoxybenzyl)benzimidazolium chloride
• CAS No.: 1009630-16-3
• Molecular Formula: C₂₇H₃₁N₂O₆*Cl
• Molecular Weight: 515.006
• Mol file: 1009630-16-3.mol

Synonyms:1,3-bis-(3,4,5-trimethoxybenzyl)benzimidazolium chloride

Chemical Property of 1,3-bis-(3,4,5-trimethoxybenzyl)benzimidazolium chloride

Chemical Property:

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Technology Process of 1,3-bis-(3,4,5-trimethoxybenzyl)benzimidazolium chloride

There total 2 articles about 1,3-bis-(3,4,5-trimethoxybenzyl)benzimidazolium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C26H32N2O6 + orthoformic acid triethyl ester (122-51-0) → 1,3-bis-(3,4,5-trimethoxybenzyl)benzimidazolium chloride (1009630-16-3)

Guidance literature:

With ammonium chloride; at 110 ℃;

DOI:10.1002/ejoc.200800007

Reference yield: 87.0%

1-(3,4,5-trimethoxybenzyl)benzimidazole + 5-(chloromethyl)-1,2,3-trimethoxybenzene (3840-30-0) → 1,3-bis-(3,4,5-trimethoxybenzyl)benzimidazolium chloride (1009630-16-3)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 5h;

DOI:10.1021/ja710276x

Reference yield: 67.0%

1,3-bis-(3,4,5-trimethoxybenzyl)benzimidazolium chloride (1009630-16-3) + methoxy(cyclooctadiene)rhodium(I) dimer → 1,3-bis[(3,4,5-trimethoxybenzyl)]-benzimidazolin-2-ylidene-[(1,2,5,6-η4)-1,5-cyclooctadiene]chlororhodium(I)

Guidance literature:

In tetrahydrofuran; for 5h; Reflux; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.jorganchem.2013.01.025

upstream raw materials:

5-(chloromethyl)-1,2,3-trimethoxybenzene

orthoformic acid triethyl ester