1,7-Bis(2-nitrophenyl)-4-thia-1,7-dioxaheptane

Base Information

• Chemical Name: 1,7-Bis(2-nitrophenyl)-4-thia-1,7-dioxaheptane
• CAS No.: 126516-86-7
• Molecular Formula: C₁₆H₁₆N₂O₆S
• Molecular Weight: 364.379
• Mol file: 126516-86-7.mol

Synonyms:1,7-Bis(2-nitrophenyl)-4-thia-1,7-dioxaheptane

Chemical Property of 1,7-Bis(2-nitrophenyl)-4-thia-1,7-dioxaheptane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,7-Bis(2-nitrophenyl)-4-thia-1,7-dioxaheptane

There total 2 articles about 1,7-Bis(2-nitrophenyl)-4-thia-1,7-dioxaheptane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,5-Dibromo-3-thiaheptane + 2-hydroxynitrobenzene (88-75-5,78813-12-4) → 1,7-Bis(2-nitrophenyl)-4-thia-1,7-dioxaheptane (126516-86-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 6h; Heating;

DOI:10.1007/BF00470035

Reference yield:

bis (2-chloroethyl) sulphide (505-60-2) + 2-hydroxynitrobenzene (88-75-5,78813-12-4) → 1,7-Bis(2-nitrophenyl)-4-thia-1,7-dioxaheptane (126516-86-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4020(01)00443-4

Reference yield:

1,7-Bis(2-nitrophenyl)-4-thia-1,7-dioxaheptane (126516-86-7) → 19-(Toluene-4-sulfonyl)-6,7,9,10,17,18,19,20,21,22-decahydro-16H-5,11-dioxa-8-thia-16,19,22-triaza-dibenzo[a,j]cyclooctadecene (126516-85-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 70 percent / NaBH₄ / 10percent Pd/C / 3 h / Heating

2: 27.5 percent

3: 57 percent / NaBH₄ / 1,2-dimethoxy-ethane

With sodium tetrahydroborate; palladium on activated charcoal; In 1,2-dimethoxyethane;

DOI:10.1007/BF00470035

upstream raw materials:

2-hydroxynitrobenzene

bis (2-chloroethyl) sulphide

Downstream raw materials:

19-(Toluene-4-sulfonyl)-6,7,9,10,17,18,19,20,21,22-decahydro-16H-5,11-dioxa-8-thia-16,19,22-triaza-dibenzo[a,j]cyclooctadecene

19-(Toluene-4-sulfonyl)-6,7,9,10,19,20-hexahydro-16H,18H,22H-5,11-dioxa-8-thia-16,19,22-triaza-dibenzo[a,j]cyclooctadecene-17,21-dione