3-O-methylfluorescein

Base Information

• Chemical Name: 3-O-methylfluorescein
• CAS No.: 70672-05-8
• Molecular Formula: C₂₁H₁₄O₅
• Molecular Weight: 346.339
• Mol file: 70672-05-8.mol

Synonyms:3-O-methylfluorescein

Chemical Property of 3-O-methylfluorescein

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-O-methylfluorescein

There total 8 articles about 3-O-methylfluorescein which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

C36H22O6 (1407780-79-3) → 3-phenyl-isocoumarin (4809-08-9) + 3-O-methylfluorescein (70672-05-8)

Guidance literature:

With gold(III) tetrachloride trihydrate; water; In acetonitrile; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1039/c2cc35083a

Reference yield:

Fmoc-Gly-MFE → N-(fluoren-9-ylmethoxycarbonyl)glycine (29022-11-5) + 3-O-methylfluorescein (70672-05-8)

Guidance literature:

With ethylenediaminetetraacetic acid; DL-dithiothreitol; cathepsin B; In phosphate buffer; at 37 ℃; pH=6.7; Enzyme kinetics;

DOI:10.1016/j.bmcl.2006.06.037

Reference yield:

Boc-Leu-MFE → N-tert-butoxycarbonyl-L-leucine (13139-15-6,53296-34-7) + 3-O-methylfluorescein (70672-05-8)

Guidance literature:

With ethylenediaminetetraacetic acid; DL-dithiothreitol; cathepsin B; In phosphate buffer; at 37 ℃; pH=6.7; Further Variations:; Reagents; Enzyme kinetics;

DOI:10.1016/j.bmcl.2006.06.037

upstream raw materials:

Boc-Ala-MFE

Boc-Abu-MFE

Fmoc-Ala-MFE

Fmoc-Abu-MFE

Downstream raw materials:

C₃₃H₂₁NO₆S₂

C₃₃H₂₁NO₈

C₃₆H₂₈O₁₀

C₃₁H₂₆O₆