Technology Process of C44H43N3
There total 14 articles about C44H43N3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
methanol; potassium carbonate;
at 23 ℃;
- Guidance literature:
-
Multi-step reaction with 12 steps
1: 12.29 g / conc. HCl, H2 / Pd/C / ethanol / 70 °C / 3102.9 Torr
2: 96 percent / 1 M NaOH / tetrahydrofuran / 2 h / Heating
3: AlCl3 / CS2 / 70 °C
4: 3 M KOH
5: aq. HCl, NaNO2 / 0.5 h / 0 °C
6: K2CO3 / 0.5 h / 0 °C
8: 99 percent / MeI / 120 °C
9: 90 percent / Pd(dba)2, Ph3P, CuI, i-Pr2NH / tetrahydrofuran / 24 h
10: 96 percent / MeI / 120 °C
11: 93 percent / Pd(dba)2, Ph3P, CuI, i-Pr2NH / tetrahydrofuran / 120 h
12: 55 percent / TBAF / tetrahydrofuran
With
hydrogenchloride; potassium hydroxide; sodium hydroxide; copper(l) iodide; aluminium trichloride; tetrabutyl ammonium fluoride; hydrogen; potassium carbonate; diisopropylamine; triphenylphosphine; bis(dibenzylideneacetone)-palladium(0); sodium nitrite; methyl iodide;
palladium on activated charcoal;
In
tetrahydrofuran; carbon disulfide; ethanol;
DOI:10.1021/jo962336q
- Guidance literature:
-
Multi-step reaction with 6 steps
2: 99 percent / MeI / 120 °C
3: 90 percent / Pd(dba)2, Ph3P, CuI, i-Pr2NH / tetrahydrofuran / 24 h
4: 96 percent / MeI / 120 °C
5: 93 percent / Pd(dba)2, Ph3P, CuI, i-Pr2NH / tetrahydrofuran / 120 h
6: 55 percent / TBAF / tetrahydrofuran
With
copper(l) iodide; tetrabutyl ammonium fluoride; diisopropylamine; triphenylphosphine; bis(dibenzylideneacetone)-palladium(0); methyl iodide;
In
tetrahydrofuran;
DOI:10.1021/jo962336q
