PSEUDOURIDINE NATURAL B ISOMER*FROM WHEAT BRAN

Base Information

• Chemical Name: PSEUDOURIDINE NATURAL B ISOMER*FROM WHEAT BRAN
• CAS No.: 10017-66-0
• Molecular Formula: C9H12 N2 O6
• Molecular Weight: 244.204
• Mol file: 10017-66-0.mol

Synonyms:Uracil,5-a-D-ribofuranosyl- (7CI,8CI);Pseudouridine B; a-Pseudouridine

Chemical Property of PSEUDOURIDINE NATURAL B ISOMER*FROM WHEAT BRAN

Chemical Property:

• PSA: 135.64000
• LogP: -2.78280

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PSEUDOURIDINE NATURAL B ISOMER*FROM WHEAT BRAN

There total 4 articles about PSEUDOURIDINE NATURAL B ISOMER*FROM WHEAT BRAN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

5-((3S,4R,5R)-3,4-Dimethoxy-5-methoxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione (78119-28-5,78119-29-6) → pseudouridine (1445-07-4) + α-pseudouridine (10017-66-0)

Guidance literature:

With boron tribromide; In dichloromethane; at -78 ℃; for 144h;

DOI:10.1039/P19810000723

Reference yield: 42.0%

5-((3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione (78119-26-3,78119-27-4) → pseudouridine (1445-07-4) + α-pseudouridine (10017-66-0)

Guidance literature:

With boron trichloride; In dichloromethane; at -78 ℃;

DOI:10.1039/P19810000723

Reference yield:

(2S,3R,4R)-2,3,5-Tris-benzyloxy-1-(2,4-di-tert-butoxy-pyrimidin-5-yl)-pentane-1,4-diol (78119-22-9,78119-23-0) → pseudouridine (1445-07-4) + α-pseudouridine (10017-66-0)

Guidance literature:

With boron trichloride; In dichloromethane; at -78 ℃; for 18h;

DOI:10.1039/P19810000723

upstream raw materials:

(1Ξ)-O²,O⁴;O³,O⁵-(R,R)-dibenzylidene-1-(2,4-bis-benzyloxy-pyrimidin-5-yl)-D-ribitol

5-((3S,4R,5R)-3,4-Dimethoxy-5-methoxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione

5-((3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione

(2S,3R,4R)-2,3,5-Tris-benzyloxy-1-(2,4-di-tert-butoxy-pyrimidin-5-yl)-pentane-1,4-diol