4,4,4-Trifluoro-3-(p-chloroanilino)-2-(p-methoxyphenyl)-2-butenenitrile

Base Information

Chemical Name:4,4,4-Trifluoro-3-(p-chloroanilino)-2-(p-methoxyphenyl)-2-butenenitrile
CAS No.:170300-51-3
Molecular Formula:C₁₇H₁₂ClF₃N₂O
Molecular Weight:352.743
Hs Code.:

Synonyms:4,4,4-Trifluoro-3-(p-chloroanilino)-2-(p-methoxyphenyl)-2-butenenitrile

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Chemical Property of 4,4,4-Trifluoro-3-(p-chloroanilino)-2-(p-methoxyphenyl)-2-butenenitrile

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Technology Process of 4,4,4-Trifluoro-3-(p-chloroanilino)-2-(p-methoxyphenyl)-2-butenenitrile

There total 1 articles about 4,4,4-Trifluoro-3-(p-chloroanilino)-2-(p-methoxyphenyl)-2-butenenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 106-47-8
4-chloro-aniline

: 4,4,4-Trifluoro-3,3-dihydroxy-2-(4-methoxy-phenyl)-butyronitrile

: 170300-51-3
4,4,4-Trifluoro-3-(p-chloroanilino)-2-(p-methoxyphenyl)-2-butenenitrile

Guidance literature:: With acetic acid; In benzene; Heating;
DOI:10.1016/0022-1139(94)03201-A

Reference yield: 16.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 170300-51-3
4,4,4-Trifluoro-3-(p-chloroanilino)-2-(p-methoxyphenyl)-2-butenenitrile

: 106-47-8
4-chloro-aniline

: 4-N-Methylamino-3H-pyrazole-3-spiro-2'-(3'-p-methoxyphenyl-3'-trifluoromethyl)oxirane

Guidance literature:: In diethyl ether; Ambient temperature;
DOI:10.1016/0022-1139(94)03201-A

Reference yield:

: 170300-51-3
4,4,4-Trifluoro-3-(p-chloroanilino)-2-(p-methoxyphenyl)-2-butenenitrile

: 170300-50-2
4,4,4-Trifluoro-3-(p-chloroanilino)-2-phenyl-2-butenenitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 16 percent / diethyl ether / Ambient temperature

2: 61 percent / acetic acid / benzene / Heating

With acetic acid; In diethyl ether; benzene;
DOI:10.1016/0022-1139(94)03201-A