1,6-Anhydro-2,3-di-O-benzyl-4-O-<(trifluormethyl)sulfonyl>-β-D-galactopyranose

Base Information

• Chemical Name: 1,6-Anhydro-2,3-di-O-benzyl-4-O-<(trifluormethyl)sulfonyl>-β-D-galactopyranose
• CAS No.: 104976-44-5
• Molecular Formula: C₂₁H₂₁F₃O₇S
• Molecular Weight: 474.455
• Mol file: 104976-44-5.mol

Synonyms:1,6-Anhydro-2,3-di-O-benzyl-4-O-<(trifluormethyl)sulfonyl>-β-D-galactopyranose

Chemical Property of 1,6-Anhydro-2,3-di-O-benzyl-4-O-<(trifluormethyl)sulfonyl>-β-D-galactopyranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,6-Anhydro-2,3-di-O-benzyl-4-O-<(trifluormethyl)sulfonyl>-β-D-galactopyranose

There total 1 articles about 1,6-Anhydro-2,3-di-O-benzyl-4-O-<(trifluormethyl)sulfonyl>-β-D-galactopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

trifluoromethylsulfonic anhydride (358-23-6) + 1,6-Anhydro-2,3-di-O-benzyl-β-D-galactopyranose (61074-29-1) → 1,6-Anhydro-2,3-di-O-benzyl-4-O-<(trifluormethyl)sulfonyl>-β-D-galactopyranose (104976-44-5)

Guidance literature:

With pyridine; In dichloromethane; at -20 ℃; for 0.5h;

Reference yield: 90.0%

1,6-Anhydro-2,3-di-O-benzyl-4-O-<(trifluormethyl)sulfonyl>-β-D-galactopyranose (104976-44-5) + 1L-(1,3/2,4)-2,3-Di-O-benzyl-1-O-methyl-tetrahydroxy-5-cyclohexen (76216-17-6) → 1,6-Anhydro-2,3-di-O-benzyl-4-O-<1L-(1,3/2,4)-2,3-di-O-benzyl-1,2,3,4-tetrahydroxy-1-O-methyl-5-cyclohexen-4-yl>-β-D-glucopyranose (104976-45-6)

Guidance literature:

With sodium hydride; 4-hydroxymethyl-3-methoxyphenoxyacetic acid; In tetrahydrofuran; at 0 - 20 ℃; for 12h;

DOI:10.1016/j.carres.2009.09.008

Reference yield: 89.0%

1,6-Anhydro-2,3-di-O-benzyl-4-O-<(trifluormethyl)sulfonyl>-β-D-galactopyranose (104976-44-5) + 1L-1,3,4,5,6-penta-O-benzyl-4-C-benzyloxymethyl-muco-inosite (122901-39-7) → 1,6-anhydro-2,3-di-O-benzyl-4-O-<1D-(1,2,4,5/3,6)-(2,3,4,5,6-penta-O-benzyl-5-C-benzyloxymethyl-2,3,4,5,6-pentahydroxy)cyclohexyl>-β-D-glucopyranose (122901-41-1)

Guidance literature:

With sodium hydride; 4-hydroxymethyl-3-methoxyphenoxyacetic acid; In tetrahydrofuran; at 0 - 20 ℃; for 17h;

DOI:10.1016/j.carres.2009.09.008

upstream raw materials:

trifluoromethylsulfonic anhydride

1,6-Anhydro-2,3-di-O-benzyl-β-D-galactopyranose

Downstream raw materials:

2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl-(1→4)-1,6-anhydro-2,3-di-O-benzyl-β-D-glucopyranose

2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl-(1→4)-1,6-anhydro-2,3-di-O-benzyl-β-D-glucopyranose

1,6-Anhydro-2,3-di-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-β-D-glucopyranose

O-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(1->4)-1,6-anhydro-2,3-di-O-benzyl-β-D-glucopyranose