Technology Process of 1-benzyl-4-(phenyl(methyl)phosphino)-1H-1,2,3-triazole
There total 4 articles about 1-benzyl-4-(phenyl(methyl)phosphino)-1H-1,2,3-triazole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1,4-diaza-bicyclo[2.2.2]octane;
In
tetrahydrofuran;
at 60 ℃;
for 3h;
Inert atmosphere;
DOI:10.1039/c4ob00397g
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium phosphate; copper(l) iodide; 1,10-Phenanthroline / toluene / 60 °C / Schlenk technique; Inert atmosphere
2: tetrabutyl ammonium fluoride / tert-butyl alcohol / 25 - 30 °C
3: copper(ll) sulfate pentahydrate; sodium L-ascorbate / water; tert-butyl alcohol / 3 h / 25 - 30 °C
4: 1,4-diaza-bicyclo[2.2.2]octane / tetrahydrofuran / 3 h / 60 °C / Inert atmosphere
With
1,4-diaza-bicyclo[2.2.2]octane; potassium phosphate; copper(l) iodide; 1,10-Phenanthroline; copper(ll) sulfate pentahydrate; tetrabutyl ammonium fluoride; sodium L-ascorbate;
In
tetrahydrofuran; water; toluene; tert-butyl alcohol;
DOI:10.1039/c4ob00397g
- Guidance literature:
-
Multi-step reaction with 2 steps
1: copper(ll) sulfate pentahydrate; sodium L-ascorbate / water; tert-butyl alcohol / 3 h / 25 - 30 °C
2: 1,4-diaza-bicyclo[2.2.2]octane / tetrahydrofuran / 3 h / 60 °C / Inert atmosphere
With
1,4-diaza-bicyclo[2.2.2]octane; copper(ll) sulfate pentahydrate; sodium L-ascorbate;
In
tetrahydrofuran; water; tert-butyl alcohol;
DOI:10.1039/c4ob00397g
