Haloprogin

Base Information

• Chemical Name: Haloprogin
• CAS No.: 777-11-7
• Molecular Formula: C9H4Cl3IO
• Molecular Weight: 361.394
• European Community (EC) Number: 212-286-6
• NSC Number: 100071
• UNII: AIU7053OWL
• DSSTox Substance ID: DTXSID9046865
• Nikkaji Number: J3.326J
• Wikipedia: Haloprogin
• Wikidata: Q5643439
• NCI Thesaurus Code: C65842
• Pharos Ligand ID: T9JBBUY3F78S
• Metabolomics Workbench ID: 43085
• ChEMBL ID: CHEMBL1289
• Mol file: 777-11-7.mol

Synonyms:3-iodo-2-propynyl 2,4,5-trichlorophenyl ether;haloprogin;Halotex;Mycilan

Chemical Property of Haloprogin

Chemical Property:

• Vapor Pressure: 5.38E-06mmHg at 25°C
• Refractive Index: 1.657
• Boiling Point: 391.9 °C at 760 mmHg
• Flash Point: 190.8 °C
• PSA: 9.23000
• Density: 1.959 g/cm³
• LogP: 4.42150
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 359.83725
• Heavy Atom Count: 14
• Complexity: 247

Purity/Quality:

99%, ^*data from raw suppliers

Haloprogin ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C(=CC(=C1Cl)Cl)Cl)OCC#CI
• Uses: Antibacterial. Haloprogin is a topical antifungal agent used in the treatment of dermatophytic and monilial infections.
• Indications: Haloprogin is used as an external drug for moderate dermatophyte infections (shingles), and it is effective for superficial candida infections. Synonyms of this drug are halotex, mycilan, micanden, and others.
• Therapeutic Function: Antibacterial

Technology Process of Haloprogin

There total 1 articles about Haloprogin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ haloprogin (777-11-7)

Guidance literature:

DOI:10.1021/jf60167a033

Reference yield:

4,4'-bipyridine (553-26-4) + haloprogin (777-11-7) → C10H8N2*2C9H4Cl3IO

Guidance literature:

In dichloromethane; at 20 ℃; for 72h;

DOI:10.1039/c4ce00367e

Reference yield:

haloprogin (777-11-7) + tetra-(n-butyl)ammonium iodide (311-28-4) → 2C9H4Cl3IO*I(1-)*C16H36N(1+)

Guidance literature:

for 0.5h; Milling;

DOI:10.1039/c4ce00367e