(E)-2-(phenylamino)nicotinaldehyde oxime

Base Information

• Chemical Name: (E)-2-(phenylamino)nicotinaldehyde oxime
• CAS No.: 1246849-53-5
• Molecular Formula: C₁₂H₁₁N₃O
• Molecular Weight: 213.239
• Mol file: 1246849-53-5.mol

Synonyms:(E)-2-(phenylamino)nicotinaldehyde oxime

Chemical Property of (E)-2-(phenylamino)nicotinaldehyde oxime

Chemical Property:

Purity/Quality:

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Technology Process of (E)-2-(phenylamino)nicotinaldehyde oxime

There total 1 articles about (E)-2-(phenylamino)nicotinaldehyde oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-phenylamino-3-pyridinecarboxaldehyde (113256-66-9) → (E)-2-(phenylamino)nicotinaldehyde oxime (1246849-53-5)

Guidance literature:

With hydroxylamine hydrochloride; In ethanol; water; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1021/ol101899q

Reference yield: 86.0%

(E)-2-(phenylamino)nicotinaldehyde oxime (1246849-53-5) → 1-phenyl-1H-pyrazolo[3,4-b]pyridine (20208-81-5)

Guidance literature:

(E)-2-(phenylamino)nicotinaldehyde oxime; With 2-aminopyridine; In dichloromethane; at 20 ℃; for 0.25h; Inert atmosphere;

With methanesulfonyl chloride; In dichloromethane; at 0 - 20 ℃; for 5h; Inert atmosphere;

DOI:10.1021/ol101899q

upstream raw materials:

2-phenylamino-3-pyridinecarboxaldehyde

Downstream raw materials:

1-phenyl-1H-pyrazolo[3,4-b]pyridine

Refernces