4-(2-Thiazolylazo)resorcinol

Base Information

• Chemical Name: 4-(2-Thiazolylazo)resorcinol
• CAS No.: 2246-46-0
• Molecular Formula: C9H7 N3 O2 S
• Molecular Weight: 221.239
• Hs Code.: 2934100090
• European Community (EC) Number: 218-836-1
• NSC Number: 298197
• DSSTox Substance ID: DTXSID40902377,DTXSID701307456
• Nikkaji Number: J207.978J
• ChEMBL ID: CHEMBL4296835,CHEMBL1433124
• Mol file: 2246-46-0.mol

Synonyms:4-(2-thiazolylazo)resorcinol

Chemical Property of 4-(2-Thiazolylazo)resorcinol

Chemical Property:

• Vapor Pressure: 3.26E-07mmHg at 25°C
• Melting Point: 211 °C (dec.)(lit.)
• Boiling Point: 402.9°Cat760mmHg
• PKA: 7.99±0.35(Predicted)
• Flash Point: 197.4°C
• PSA: 106.31000
• Density: 1.53g/cm³
• LogP: 2.96970
• Solubility.: almost transparency in hot EtOH50vol%
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 221.02589765
• Heavy Atom Count: 15
• Complexity: 239

Purity/Quality:

97% ^*data from raw suppliers

4-(2-Thiazolylazo)resorcinol ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1O)O)N=NC2=NC=CS2
• Description: A dark, viscous,usually pungent substance, tar is derived from the destructive distillation of various organic compounds such as wood,coal, or shale,that is used for various industrial purposes.
• Uses: 4-(2-Thiazolylazo)resorcinol is used in treatment of psoriasis.

Technology Process of 4-(2-Thiazolylazo)resorcinol

There total 3 articles about 4-(2-Thiazolylazo)resorcinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-thiazolylamine (96-50-4) + recorcinol (108-46-3) → 4-(thiazol-2-ylazo)resorcinol (2246-46-0)

Guidance literature:

Multistep reaction; (i) aq. NaNO₂, HCl, (ii) /BRN= 906905/, (iii) aq. NaOAc;

Reference yield:

recorcinol (108-46-3) → 4-(thiazol-2-ylazo)resorcinol (2246-46-0)

Guidance literature:

Reference yield:

→ 4-(thiazol-2-ylazo)resorcinol (2246-46-0)

Guidance literature:

Diazot. 2-Aminothiazol, Resorcin, wss. HCl (0grad);

upstream raw materials:

2-thiazolylamine

recorcinol

Downstream raw materials:

Mn⁽²⁺⁾*C₉H₆N₃O₂S^(1-)*Cl^(1-)=Mn(C₉H₆N₃O₂S)Cl