5-[2-(3-chloro-phenyl)-vinyl]-3-phenyl-2-(toluene-4-sulfonyl)-3,4-dihydro-2H-pyrazol-3-ol

Base Information

• Chemical Name: 5-[2-(3-chloro-phenyl)-vinyl]-3-phenyl-2-(toluene-4-sulfonyl)-3,4-dihydro-2H-pyrazol-3-ol
• CAS No.: 1055302-46-9
• Molecular Formula: C₂₄H₂₁ClN₂O₃S
• Molecular Weight: 452.961
• Mol file: 1055302-46-9.mol

Synonyms:5-[2-(3-chloro-phenyl)-vinyl]-3-phenyl-2-(toluene-4-sulfonyl)-3,4-dihydro-2H-pyrazol-3-ol

Chemical Property of 5-[2-(3-chloro-phenyl)-vinyl]-3-phenyl-2-(toluene-4-sulfonyl)-3,4-dihydro-2H-pyrazol-3-ol

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 5-[2-(3-chloro-phenyl)-vinyl]-3-phenyl-2-(toluene-4-sulfonyl)-3,4-dihydro-2H-pyrazol-3-ol

There total 1 articles about 5-[2-(3-chloro-phenyl)-vinyl]-3-phenyl-2-(toluene-4-sulfonyl)-3,4-dihydro-2H-pyrazol-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

(E)-3-(3-Chloro-phenyl)-1-(3-phenyl-oxiranyl)-propenone + toluene-4-sulfonic acid hydrazide (1576-35-8) → 3-[2-(3-chloro-phenyl)-vinyl]-5-phenyl-1-(toluene-4-sulfonyl)-1H-pyrazole + 5-[2-(3-chloro-phenyl)-vinyl]-3-phenyl-2-(toluene-4-sulfonyl)-3,4-dihydro-2H-pyrazol-3-ol (1055302-46-9)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; at 20 ℃;

DOI:10.1055/s-2005-862353

Reference yield:

5-[2-(3-chloro-phenyl)-vinyl]-3-phenyl-2-(toluene-4-sulfonyl)-3,4-dihydro-2H-pyrazol-3-ol (1055302-46-9) → 3-[2-(3-chloro-phenyl)-vinyl]-5-phenyl-1-(toluene-4-sulfonyl)-1H-pyrazole

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; at 50 ℃; for 6h;

DOI:10.1055/s-2005-862353

Reference yield:

5-[2-(3-chloro-phenyl)-vinyl]-3-phenyl-2-(toluene-4-sulfonyl)-3,4-dihydro-2H-pyrazol-3-ol (1055302-46-9) + propylamine (107-10-8,42939-71-9) → [5-[2-(3-chloro-phenyl)-vinyl]-3-phenyl-2-(toluene-4-sulfonyl)-3,4-dihydro-2H-pyrazol-3-yl]-propyl-amine

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 12h;

DOI:10.1055/s-2005-862353

upstream raw materials:

toluene-4-sulfonic acid hydrazide