3-cyclopropylpyrazin-2-amine

Base Information

• Chemical Name: 3-cyclopropylpyrazin-2-amine
• CAS No.: 1190969-76-6
• Molecular Formula: C₇H₉N₃
• Molecular Weight: 135.169
• Hs Code.: 2933998090
• Mol file: 1190969-76-6.mol

Synonyms:3-cyclopropylpyrazin-2-amine

Chemical Property of 3-cyclopropylpyrazin-2-amine

Chemical Property:

• Boiling Point: 269.1±40.0 °C(Predicted)
• PKA: 3.56±0.10(Predicted)
• Density: 1.273±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

3-Cyclopropylpyrazin-2-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-cyclopropylpyrazin-2-amine

There total 1 articles about 3-cyclopropylpyrazin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C16H19N3O2 (1215039-55-6) → 3-cyclopropylpyrazin-2-amine (1190969-76-6)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; for 16h;

DOI:10.1016/j.bmcl.2009.07.021

Reference yield: 68.0%

(3-bromo-1-(R)-methyl-2-oxopropyl)carbamic acid benzyl ester (852248-32-9) + 3-cyclopropylpyrazin-2-amine (1190969-76-6) → C19H20N4O2 (1190969-77-7)

Guidance literature:

With potassium carbonate; In acetonitrile; at 75 ℃; for 16h;

DOI:10.1016/j.bmcl.2009.07.021

upstream raw materials:

C₁₆H₁₉N₃O₂

Downstream raw materials:

C₁₉H₂₀N₄O₂

Refernces