5-fluoro-1-uracil

Base Information

• Chemical Name: 5-fluoro-1-uracil
• CAS No.: 124360-93-6
• Molecular Formula: C₁₁H₉FN₄O₂S
• Molecular Weight: 280.282

Synonyms:5-fluoro-1-uracil

Chemical Property of 5-fluoro-1-uracil

Chemical Property:

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Technology Process of 5-fluoro-1-uracil

There total 1 articles about 5-fluoro-1-uracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

phenyl isothiocyanate (103-72-0) + 1-amino-5-fluorouracil hydrochloride → 5-fluoro-1-uracil (124360-93-6)

Guidance literature:

In pyridine; for 4h; Ambient temperature;

DOI:10.1246/bcsj.62.674

Reference yield:

5-fluoro-1-uracil (124360-93-6) → 5-fluorouracil (51-21-8)

Guidance literature:

In methanol; water; Kinetics; Ambient temperature; Irradiation; rate constant; other solvents;

DOI:10.1246/cl.1989.707

upstream raw materials:

phenyl isothiocyanate

Downstream raw materials:

5-fluorouracil

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