N-(2-hydroxybenzyl)-N-methylhydrazine

Base Information

• Chemical Name: N-(2-hydroxybenzyl)-N-methylhydrazine
• CAS No.: 5638-98-2
• Molecular Formula: C8H12 N2 O
• Molecular Weight: 152.196
• Mol file: 5638-98-2.mol

Synonyms:Phenol,2-[(1-methylhydrazino)methyl]- (9CI); o-Cresol, a-(1-methylhydrazino)- (7CI,8CI);N-(2-Hydroxybenzyl)-N-methyl hydrazine; NSD 1039; Phenol,2-(2-methylhydrazinyl)-

Chemical Property of N-(2-hydroxybenzyl)-N-methylhydrazine

Chemical Property:

• Vapor Pressure: 0.000414mmHg at 25°C
• Boiling Point: 306.9°Cat760mmHg
• Flash Point: 139.4°C
• PSA: 49.49000
• Density: 1.156g/cm³
• LogP: 1.39800

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(2-hydroxybenzyl)-N-methylhydrazine

There total 3 articles about N-(2-hydroxybenzyl)-N-methylhydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C13H20N2O3 (1017319-36-6) → 2-(N-Methyl-hydrazinomethyl)-phenol (5638-98-2)

Guidance literature:

With hydrogenchloride; In methanol;

DOI:10.1002/anie.200703857

Reference yield:

N-nitrozo(o-hydroxybenzyl)methylamine (90007-13-9) → 2-(N-Methyl-hydrazinomethyl)-phenol (5638-98-2)

Guidance literature:

With acetic acid; zinc;

Reference yield:

2-methylaminomethyl-phenol; hydrochloride (63989-87-7) → 2-(N-Methyl-hydrazinomethyl)-phenol (5638-98-2)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium nitrite

2: acetic acid; zinc

With acetic acid; zinc; sodium nitrite;

upstream raw materials:

N-nitrozo(o-hydroxybenzyl)methylamine

2-methylaminomethyl-phenol; hydrochloride

C₁₃H₂₀N₂O₃

Downstream raw materials:

C₁₆H₁₈N₂O₂

C₁₅H₁₇N₃O₂

C₁₅H₂₆N₃O₂⁽¹⁺⁾*Cl^(1-)

C₁₃H₂₂N₃O₂⁽¹⁺⁾*Cl^(1-)