(+)-(1R,3S)-N-benzyl-N-[2,2-dimethyl-3-(2-methyl-1H-indol-3-yl)cyclopropylmethyl]cyanamide

Base Information

Chemical Name:(+)-(1R,3S)-N-benzyl-N-[2,2-dimethyl-3-(2-methyl-1H-indol-3-yl)cyclopropylmethyl]cyanamide
CAS No.:496029-90-4
Molecular Formula:C₂₃H₂₅N₃
Molecular Weight:343.472
Hs Code.:

Synonyms:(+)-(1R,3S)-N-benzyl-N-[2,2-dimethyl-3-(2-methyl-1H-indol-3-yl)cyclopropylmethyl]cyanamide

Suppliers and Price of (+)-(1R,3S)-N-benzyl-N-[2,2-dimethyl-3-(2-methyl-1H-indol-3-yl)cyclopropylmethyl]cyanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (+)-(1R,3S)-N-benzyl-N-[2,2-dimethyl-3-(2-methyl-1H-indol-3-yl)cyclopropylmethyl]cyanamide

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Technology Process of (+)-(1R,3S)-N-benzyl-N-[2,2-dimethyl-3-(2-methyl-1H-indol-3-yl)cyclopropylmethyl]cyanamide

There total 2 articles about (+)-(1R,3S)-N-benzyl-N-[2,2-dimethyl-3-(2-methyl-1H-indol-3-yl)cyclopropylmethyl]cyanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: Benzyl-{(1R,3S)-2,2-dimethyl-3-[2-(phenyl-hydrazono)-propyl]-cyclopropylmethyl}-cyanamide

: 496029-90-4
(+)-(1R,3S)-N-benzyl-N-[2,2-dimethyl-3-(2-methyl-1H-indol-3-yl)cyclopropylmethyl]cyanamide

Guidance literature:: With PPE; In dichloromethane; at 20 ℃; for 12h;
DOI:10.1023/A:1020969017314

Reference yield:

: 298201-64-6
Benzyl[(1R,3S)-2,2-dimethyl-3-(2-oxopropyl)cyclopropylmethyl]cyanamide

: 496029-90-4
(+)-(1R,3S)-N-benzyl-N-[2,2-dimethyl-3-(2-methyl-1H-indol-3-yl)cyclopropylmethyl]cyanamide

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 2 h / 20 °C

2: 0.16 g / PPE / CH₂Cl₂ / 12 h / 20 °C

With PPE; In methanol; dichloromethane; 2: Fischer indole synthesis;
DOI:10.1023/A:1020969017314