N-(4-methoxybenzyl)-N-[7-(benzyloxy)quinolin-3-yl]-4-methoxy-3-(3-methoxyphenyl)benzamide

Base Information

• Chemical Name: N-(4-methoxybenzyl)-N-[7-(benzyloxy)quinolin-3-yl]-4-methoxy-3-(3-methoxyphenyl)benzamide
• CAS No.: 1083313-82-9
• Molecular Formula: C₃₉H₃₄N₂O₅
• Molecular Weight: 610.709

Synonyms:N-(4-methoxybenzyl)-N-[7-(benzyloxy)quinolin-3-yl]-4-methoxy-3-(3-methoxyphenyl)benzamide

Chemical Property of N-(4-methoxybenzyl)-N-[7-(benzyloxy)quinolin-3-yl]-4-methoxy-3-(3-methoxyphenyl)benzamide

Chemical Property:

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Technology Process of N-(4-methoxybenzyl)-N-[7-(benzyloxy)quinolin-3-yl]-4-methoxy-3-(3-methoxyphenyl)benzamide

There total 1 articles about N-(4-methoxybenzyl)-N-[7-(benzyloxy)quinolin-3-yl]-4-methoxy-3-(3-methoxyphenyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

3',6-dimethoxy-[1,1'-biphenyl]-3-carbonyl chloride (1083313-80-7) + N-(4-methoxybenzyl)-7-(benzyloxy)quinolin-3-amine (1083313-78-3) → N-(4-methoxybenzyl)-N-[7-(benzyloxy)quinolin-3-yl]-4-methoxy-3-(3-methoxyphenyl)benzamide (1083313-82-9)

Guidance literature:

N-(4-methoxybenzyl)-7-(benzyloxy)quinolin-3-amine; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 2h;

3',6-dimethoxy-[1,1'-biphenyl]-3-carbonyl chloride; In tetrahydrofuran; for 18h; Reflux;

DOI:10.1021/jo801312r

Reference yield: 100.0%

N-(4-methoxybenzyl)-N-[7-(benzyloxy)quinolin-3-yl]-4-methoxy-3-(3-methoxyphenyl)benzamide (1083313-82-9) → N-(4-methoxybenzyl)-N-(7-hydroxyquinolin-3-yl)-4-methoxy-3-(3-methoxyphenyl)benzamide (1083313-84-1)

Guidance literature:

With aluminum (III) chloride; methoxybenzene; at 20 ℃; for 18h;

DOI:10.1021/jo801312r

upstream raw materials:

3',6-dimethoxy-[1,1'-biphenyl]-3-carbonyl chloride

N-(4-methoxybenzyl)-7-(benzyloxy)quinolin-3-amine

Downstream raw materials:

N-(4-methoxybenzyl)-N-(7-hydroxyquinolin-3-yl)-4-methoxy-3-(3-methoxyphenyl)benzamide

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