(S)-N-((3-(3-fluoro-4-(1-carbamoyl-[1,2,5]triazepan-5-yl)phenyl)-2-oxo-5-oxazolidinyl)methyl)thioacetamide

Base Information

Chemical Name:(S)-N-((3-(3-fluoro-4-(1-carbamoyl-[1,2,5]triazepan-5-yl)phenyl)-2-oxo-5-oxazolidinyl)methyl)thioacetamide
CAS No.:1138148-66-9
Molecular Formula:C₁₇H₂₃FN₆O₃S
Molecular Weight:410.472
Hs Code.:

Synonyms:(S)-N-((3-(3-fluoro-4-(1-carbamoyl-[1,2,5]triazepan-5-yl)phenyl)-2-oxo-5-oxazolidinyl)methyl)thioacetamide

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Chemical Property of (S)-N-((3-(3-fluoro-4-(1-carbamoyl-[1,2,5]triazepan-5-yl)phenyl)-2-oxo-5-oxazolidinyl)methyl)thioacetamide

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Technology Process of (S)-N-((3-(3-fluoro-4-(1-carbamoyl-[1,2,5]triazepan-5-yl)phenyl)-2-oxo-5-oxazolidinyl)methyl)thioacetamide

There total 2 articles about (S)-N-((3-(3-fluoro-4-(1-carbamoyl-[1,2,5]triazepan-5-yl)phenyl)-2-oxo-5-oxazolidinyl)methyl)thioacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₂H₃₁FN₆O₅S

: 1138148-66-9
(S)-N-((3-(3-fluoro-4-(1-carbamoyl-[1,2,5]triazepan-5-yl)phenyl)-2-oxo-5-oxazolidinyl)methyl)thioacetamide

Guidance literature:: With hydrogenchloride; water; In 1,4-dioxane; at 20 ℃; for 1h;
DOI:10.1016/j.ejmech.2013.08.002

Reference yield:

: 1443005-47-7
5(S)-(thioacetylaminomethyl)-3-(3-fluoro-4-(1-(tertbutoxycarbonyl)[1,2,5]triazepan-5-yl)phenyl)oxazolidin-2-one

: 1138148-66-9
(S)-N-((3-(3-fluoro-4-(1-carbamoyl-[1,2,5]triazepan-5-yl)phenyl)-2-oxo-5-oxazolidinyl)methyl)thioacetamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / tetrahydrofuran / 0.17 h / 0 °C

1.2: 20 h / 20 °C

2.1: hydrogenchloride; water / 1,4-dioxane / 1 h / 20 °C

With hydrogenchloride; water; triethylamine; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1016/j.ejmech.2013.08.002