(S)-2-(((2R,3S)-3-((tert-butyldimethylsilyloxy)methyl)aziridin-2-yl)methylamino)-4-methyl-N-phenylpentanamide

Base Information

Chemical Name:(S)-2-(((2R,3S)-3-((tert-butyldimethylsilyloxy)methyl)aziridin-2-yl)methylamino)-4-methyl-N-phenylpentanamide
CAS No.:1000072-72-9
Molecular Formula:C₂₂H₃₉N₃O₂Si
Molecular Weight:405.656
Hs Code.:

Synonyms:(S)-2-(((2R,3S)-3-((tert-butyldimethylsilyloxy)methyl)aziridin-2-yl)methylamino)-4-methyl-N-phenylpentanamide

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Chemical Property of (S)-2-(((2R,3S)-3-((tert-butyldimethylsilyloxy)methyl)aziridin-2-yl)methylamino)-4-methyl-N-phenylpentanamide

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Technology Process of (S)-2-(((2R,3S)-3-((tert-butyldimethylsilyloxy)methyl)aziridin-2-yl)methylamino)-4-methyl-N-phenylpentanamide

There total 2 articles about (S)-2-(((2R,3S)-3-((tert-butyldimethylsilyloxy)methyl)aziridin-2-yl)methylamino)-4-methyl-N-phenylpentanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1021177-50-3
C₁₀H₂₁NO₂Si

: 21930-98-3
(S)-2-amino-4-methyl-N-phenylpentanamide

: 1000072-72-9
(S)-2-(((2R,3S)-3-((tert-butyldimethylsilyloxy)methyl)aziridin-2-yl)methylamino)-4-methyl-N-phenylpentanamide

Guidance literature:: C₁₀H₂₁NO₂Si; (S)-2-amino-4-methyl-N-phenylpentanamide; With zinc(II) chloride; In tetrahydrofuran; methanol; dichloromethane; at 20 ℃; for 0.0166667h;

With sodium cyanoborohydride; In tetrahydrofuran; methanol; dichloromethane; at 20 ℃;

Reference yield: 84.0%

: C₂₀H₄₂N₂O₄Si₂

: 21930-98-3
(S)-2-amino-4-methyl-N-phenylpentanamide

: 1000072-72-9
(S)-2-(((2R,3S)-3-((tert-butyldimethylsilyloxy)methyl)aziridin-2-yl)methylamino)-4-methyl-N-phenylpentanamide

Guidance literature:: With sodium cyanoborohydride; zinc(II) chloride; In tetrahydrofuran; methanol; dichloromethane; at 20 ℃;
DOI:10.1021/ja076155p