Technology Process of 2-azido-4-bromobenzoic acid
There total 3 articles about 2-azido-4-bromobenzoic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2-amino-4-bromobenzoic acid;
With
hydrogenchloride;
In
water;
at 5 - 80 ℃;
for 0.5h;
With
sodium nitrite;
In
water;
at 0 ℃;
for 1h;
With
sodium azide; sodium ethanolate;
In
water;
at 20 ℃;
for 3h;
- Guidance literature:
-
With
sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene;
In
tetrahydrofuran; water; tert-butyl alcohol;
at 0 - 20 ℃;
DOI:10.1016/j.tetlet.2021.152828
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium azide / dimethyl sulfoxide / 50 °C
2: 2-methyl-but-2-ene; sodium chlorite; sodium dihydrogenphosphate / tetrahydrofuran; tert-butyl alcohol; water / 0 - 20 °C
With
sodium chlorite; sodium dihydrogenphosphate; sodium azide; 2-methyl-but-2-ene;
In
tetrahydrofuran; water; dimethyl sulfoxide; tert-butyl alcohol;
DOI:10.1016/j.tetlet.2021.152828
