C₂₃H₁₇ClN₂O

Base Information

Chemical Name:C₂₃H₁₇ClN₂O
CAS No.:1381766-45-5
Molecular Formula:C₂₃H₁₇ClN₂O
Molecular Weight:372.854
Hs Code.:

C<sub>23</sub>H<sub>17</sub>ClN<sub>2</sub>O

Synonyms:C₂₃H₁₇ClN₂O

Suppliers and Price of C₂₃H₁₇ClN₂O

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₂₃H₁₇ClN₂O

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₂₃H₁₇ClN₂O

There total 6 articles about C₂₃H₁₇ClN₂O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 1381766-63-7
2-((4-chloro-2-(dimethylamino)phenyl)ethynyl)-N-(p-tolyl)benzamide

: 1381766-45-5
C₂₃H₁₇ClN₂O

Guidance literature:: With palladium diacetate; tetra-(n-butyl)ammonium iodide; acetic acid; In dimethyl sulfoxide; at 50 ℃; for 12h; under 760.051 Torr; chemoselective reaction;
DOI:10.1002/anie.201201640

Reference yield:

: 1369940-23-7
5-chloro-2-iodo-N,N-dimethylaniline

: 1381766-45-5
C₂₃H₁₇ClN₂O

Guidance literature:: Multi-step reaction with 4 steps

1.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere

2.1: sodium hydroxide / methanol; diethyl ether; water / 0.17 h / 20 °C

3.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / N,N-dimethyl-formamide / 0.17 h / Inert atmosphere

3.2: 80 - 85 °C / Inert atmosphere

4.1: palladium diacetate; tetra-(n-butyl)ammonium iodide; acetic acid / dimethyl sulfoxide / 12 h / 50 °C / 760.05 Torr

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; palladium diacetate; tetra-(n-butyl)ammonium iodide; acetic acid; triethylamine; sodium hydroxide; In methanol; diethyl ether; water; dimethyl sulfoxide; N,N-dimethyl-formamide; 1.1: Sonogashira coupling / 3.1: Sonogashira coupling / 3.2: Sonogashira coupling;
DOI:10.1002/anie.201201640

Reference yield:

: 1381766-72-8
5-chloro-N,N-dimethyl-2-((trimethylsilyl)ethynyl)aniline

: 1381766-45-5
C₂₃H₁₇ClN₂O

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydroxide / methanol; diethyl ether; water / 0.17 h / 20 °C

2.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / N,N-dimethyl-formamide / 0.17 h / Inert atmosphere

2.2: 80 - 85 °C / Inert atmosphere

3.1: palladium diacetate; tetra-(n-butyl)ammonium iodide; acetic acid / dimethyl sulfoxide / 12 h / 50 °C / 760.05 Torr

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; palladium diacetate; tetra-(n-butyl)ammonium iodide; acetic acid; triethylamine; sodium hydroxide; In methanol; diethyl ether; water; dimethyl sulfoxide; N,N-dimethyl-formamide; 2.1: Sonogashira coupling / 2.2: Sonogashira coupling;
DOI:10.1002/anie.201201640