1-((trans)-4-(1-bromo-8-methylimidazo[1,5-a]pyrazin-3-yl)cyclohexyl)-N-methylmethanamine

Base Information

Chemical Name:1-((trans)-4-(1-bromo-8-methylimidazo[1,5-a]pyrazin-3-yl)cyclohexyl)-N-methylmethanamine
CAS No.:1326283-07-1
Molecular Formula:C₁₅H₂₁BrN₄
Molecular Weight:337.263
Hs Code.:

Synonyms:1-((trans)-4-(1-bromo-8-methylimidazo[1,5-a]pyrazin-3-yl)cyclohexyl)-N-methylmethanamine

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Chemical Property of 1-((trans)-4-(1-bromo-8-methylimidazo[1,5-a]pyrazin-3-yl)cyclohexyl)-N-methylmethanamine

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Technology Process of 1-((trans)-4-(1-bromo-8-methylimidazo[1,5-a]pyrazin-3-yl)cyclohexyl)-N-methylmethanamine

There total 3 articles about 1-((trans)-4-(1-bromo-8-methylimidazo[1,5-a]pyrazin-3-yl)cyclohexyl)-N-methylmethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1326283-06-0
benzyl ((trans)-4-(1-bromo-8-methylimidazo[1,5-a]pyrazin-3-yl)cyclohexyl)methyl(methyl)carbamate

: 1326283-07-1
1-((trans)-4-(1-bromo-8-methylimidazo[1,5-a]pyrazin-3-yl)cyclohexyl)-N-methylmethanamine

Guidance literature:: benzyl ((trans)-4-(1-bromo-8-methylimidazo[1,5-a]pyrazin-3-yl)cyclohexyl)methyl(methyl)carbamate; With hydrogenchloride; water; at 40 ℃; for 1h;

With sodium hydroxide; In water;

Reference yield:

: 1326282-98-7
benzyl ((trans)-4-(1-bromo-8-methylimidazo[1,5-a]pyrazin-3-yl)cyclohexyl)methylcarbamate

: 1326283-07-1
1-((trans)-4-(1-bromo-8-methylimidazo[1,5-a]pyrazin-3-yl)cyclohexyl)-N-methylmethanamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.08 h

1.2: 18 h / 20 °C

2.1: hydrogenchloride; water / 1 h / 40 °C

With hydrogenchloride; water; sodium hydride; In N,N-dimethyl-formamide; mineral oil;

Reference yield:

: 1326282-97-6
benzyl ((trans)-4-(8-methylimidazo[1,5-a]pyrazin-3-yl)cyclohexyl)methylcarbamate

: 1326283-07-1
1-((trans)-4-(1-bromo-8-methylimidazo[1,5-a]pyrazin-3-yl)cyclohexyl)-N-methylmethanamine

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-Bromosuccinimide / N,N-dimethyl-formamide / 4 h / 20 °C

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.08 h

2.2: 18 h / 20 °C

3.1: hydrogenchloride; water / 1 h / 40 °C

With hydrogenchloride; N-Bromosuccinimide; water; sodium hydride; In N,N-dimethyl-formamide; mineral oil;