pilocarpic acid 4-methylbenzyl ester

Base Information

• Chemical Name: pilocarpic acid 4-methylbenzyl ester
• CAS No.: 92598-93-1
• Molecular Formula: C₁₉H₂₆N₂O₃
• Molecular Weight: 330.427
• Mol file: 92598-93-1.mol

Synonyms:pilocarpic acid 4-methylbenzyl ester

Chemical Property of pilocarpic acid 4-methylbenzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of pilocarpic acid 4-methylbenzyl ester

There total 2 articles about pilocarpic acid 4-methylbenzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

O-benzoyl pilocarpic acid 4-methylbenzyl ester → pilocarpic acid 4-methylbenzyl ester (92598-93-1) + pilocarpine (92-13-7)

Guidance literature:

With 75percent human plasma; at 37 ℃; Product distribution; time dependence;

DOI:10.1002/jps.2600750811

Reference yield:

pilocarpine hydrochloride (54-71-7) → pilocarpic acid 4-methylbenzyl ester (92598-93-1)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NaOH / H₂O / 1 h / 0 - 4 °C

2: 40 percent / dimethylformamide / Ambient temperature

With sodium hydroxide; In water; N,N-dimethyl-formamide;

DOI:10.1002/jps.2600750109

Reference yield:

pilocarpic acid 4-methylbenzyl ester (92598-93-1) → pilocarpine (92-13-7)

Guidance literature:

With phosphate buffer; at 37 ℃; Rate constant; pH 7.40;

DOI:10.1002/jps.2600750109

upstream raw materials:

pilocarpine hydrochloride

Downstream raw materials:

pilocarpine