tert-butyl (S)-2-((4-(N-((benzyloxy)carbonyl)carbamimidoyl)benzyl)carbamoyl)azetidine-1-carboxylate

Base Information

Chemical Name:tert-butyl (S)-2-((4-(N-((benzyloxy)carbonyl)carbamimidoyl)benzyl)carbamoyl)azetidine-1-carboxylate
CAS No.:187752-05-2
Molecular Formula:C₂₅H₃₀N₄O₅
Molecular Weight:466.537
Hs Code.:

Synonyms:tert-butyl (S)-2-((4-(N-((benzyloxy)carbonyl)carbamimidoyl)benzyl)carbamoyl)azetidine-1-carboxylate

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Chemical Property of tert-butyl (S)-2-((4-(N-((benzyloxy)carbonyl)carbamimidoyl)benzyl)carbamoyl)azetidine-1-carboxylate

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Technology Process of tert-butyl (S)-2-((4-(N-((benzyloxy)carbonyl)carbamimidoyl)benzyl)carbamoyl)azetidine-1-carboxylate

There total 1 articles about tert-butyl (S)-2-((4-(N-((benzyloxy)carbonyl)carbamimidoyl)benzyl)carbamoyl)azetidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 187752-05-2
tert-butyl (S)-2-((4-(N-((benzyloxy)carbonyl)carbamimidoyl)benzyl)carbamoyl)azetidine-1-carboxylate

Guidance literature:: With 1-hydroxy-pyrrolidine-2,5-dione; In dichloromethane; at 20 ℃;

With dicyclohexyl-carbodiimide; In dichloromethane; for 1h;

In dichloromethane; at 20 ℃; Sonication;

Reference yield: 87.0%

: 433938-94-4
Ph(3-Cl)(5-OCH₂CHF₂)-(R)CH(OH)C(O)OH

: 187752-05-2
Boc-Aze-Pab(Z)

: 433939-57-2
Ph(3-Cl)(5-OCH₂CHF₂)-(R)CH(OH)C(O)-Aze-Pab(Z)

Guidance literature:: Boc-Aze-Pab(Z); With hydrogenchloride; In ethyl acetate; for 0.166667h;

Ph(3-Cl)(5-OCH₂CHF₂)-(R)CH(OH)C(O)OH; With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); for 2h;

Reference yield: 79.0%

: 433939-16-3
Ph(3-Cl)(5-OCH₂CH₂F)-(R)CH(OH)C(O)OH

: 187752-05-2
Boc-Aze-Pab(Z)

: 433939-58-3
Ph(3-Cl)(5-OCH₂CH₂F)-(R)CH(OH)C(O)-Aze-Pab(Z)

Guidance literature:: Boc-Aze-Pab(Z); With hydrogenchloride; In ethyl acetate; for 0.166667h;

Ph(3-Cl)(5-OCH₂CH₂F)-(R)CH(OH)C(O)OH; With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); for 2.16667h;