Technology Process of C15H14F3N3O3
There total 7 articles about C15H14F3N3O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C20H22F3N3O5;
With
trifluoroacetic acid;
In
1,2-dichloro-ethane;
at 0 ℃;
for 0.25h;
With
sodium hydrogencarbonate;
In
water; 1,2-dichloro-ethane;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: water; iron; ammonium chloride / ethanol / 0.83 h / 100 - 105 °C
2.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C
2.2: 0 - 20 °C
2.3: 2 h / 20 °C
3.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -78 °C
3.2: -78 - 20 °C
4.1: trifluoroacetic acid / 1,2-dichloro-ethane / 0.25 h / 0 °C
With
water; iron; sodium hydride; ammonium chloride; trifluoroacetic acid; lithium hexamethyldisilazane;
In
tetrahydrofuran; ethanol; 1,2-dichloro-ethane;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: N-ethyl-N,N-diisopropylamine / 1-methylpiperidin-2-one / -10 - 20 °C
2.1: triethylamine / tetrahydrofuran / 2.67 h / 0 - 20 °C
3.1: ammonium cerium(IV) nitrate / N,N-dimethyl-formamide / 4 h / 0 - 20 °C
4.1: water; iron; ammonium chloride / ethanol / 0.83 h / 100 - 105 °C
5.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C
5.2: 0 - 20 °C
5.3: 2 h / 20 °C
6.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -78 °C
6.2: -78 - 20 °C
7.1: trifluoroacetic acid / 1,2-dichloro-ethane / 0.25 h / 0 °C
With
ammonium cerium(IV) nitrate; water; iron; sodium hydride; ammonium chloride; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; lithium hexamethyldisilazane;
In
tetrahydrofuran; 1-methylpiperidin-2-one; ethanol; 1,2-dichloro-ethane; N,N-dimethyl-formamide;