Abacavir succinate

Base Information

• Chemical Name: Abacavir succinate
• CAS No.: 168146-84-7
• Molecular Formula: C18H24N6O5
• Molecular Weight: 0
• UNII: 40FH6D8CHK
• Wikidata: Q27258326
• NCI Thesaurus Code: C71608
• ChEMBL ID: CHEMBL2106686
• Mol file: 168146-84-7.mol

Synonyms:((1R,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-cyclopent-2-enyl)methanol;((1R,4S)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methanol;(+)-abacavir;(+)-abacavir sulfate;(+-)-abacavir sulfate;(-)-cis-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-2-cyclopentene-1-methanol;(1R,4R)-abacavir;(1R,4S)-abacavir sulfate;(1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-2-cyclopentene-1-methanol;(1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-2-cyclopentene-1-methanol succinate (1:1) (salt);1592U89;2-cyclopentene-1-methanol, 4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-, (1R,4S)-, sulfate (2:1);2-cyclopentene-1-methanol, 4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-, (1S,4R)-, rel-, sulfate (2:1);2-cyclopentene-1-methanol, 4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-, hydrochloride, hydrate (1:1:1), (1S,4R)-;abacavir;abacavir enantiomer;abacavir hydrochloride monohydrate;abacavir succinate;abacavir sulfate;abacavir sulfate racemic;abacavir sulfate, (+)-;abacavir sulfate, (+-)-;abacavir sulfate, (1R,4S)-;abacavir sulphate;abacavir, (+)-;abacavir, (1R,4S)-;abacavir, trans-;abacavir, trans-, (+-)-;Abamune;avacavir;DRG 0257;DRG-0257;DRG0257;trans-abacavir;trans-abacavir R,R-;Ziagen

Chemical Property of Abacavir succinate

Chemical Property:

• Boiling Point: 1095.4°Cat760mmHg
• Flash Point: 616.3°C
• PSA: 46.53000
• Density: g/cm³
• LogP: 0.87660
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 7
• Exact Mass: 404.18081789
• Heavy Atom Count: 29
• Complexity: 507

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)C4CC(C=C4)CO.C(CC(=O)O)C(=O)O
• Isomeric SMILES: C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)CO.C(CC(=O)O)C(=O)O
• Uses: Antiviral.

Technology Process of Abacavir succinate

There total 1 articles about Abacavir succinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

→ (1S,4R)-cis -4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclo-pentene-1-methanol Succinate Salt + Abacavir succinate (168146-84-7)

Guidance literature:

Refernces