Technology Process of C45H54N8O11S
There total 4 articles about C45H54N8O11S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
at 0 - 20 ℃;
DOI:10.1016/j.tet.2007.06.103
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 91 percent / formic acid / 2 h / Heating
2.1: NaHCO3 / tetrahydrofuran / 8 h / 20 °C
2.2: 62 percent / TFAA; lutidine / tetrahydrofuran / -10 - 20 °C
3.1: 100 percent / LiOH / tetrahydrofuran; H2O; methanol / 1 h / 20 °C
4.1: 70 percent / EDC*HCl; HOBt; N,N-diisopropylethylamine / CH2Cl2 / 0 - 20 °C
With
lithium hydroxide; formic acid; sodium hydrogencarbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; methanol; dichloromethane; water;
2.2: Hantzsch thiazole synthesis;
DOI:10.1016/j.tet.2007.06.103
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: NaHCO3 / tetrahydrofuran / 8 h / 20 °C
1.2: 62 percent / TFAA; lutidine / tetrahydrofuran / -10 - 20 °C
2.1: 100 percent / LiOH / tetrahydrofuran; H2O; methanol / 1 h / 20 °C
3.1: 70 percent / EDC*HCl; HOBt; N,N-diisopropylethylamine / CH2Cl2 / 0 - 20 °C
With
lithium hydroxide; sodium hydrogencarbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; methanol; dichloromethane; water;
1.2: Hantzsch thiazole synthesis;
DOI:10.1016/j.tet.2007.06.103
