(S)-((R)-3-(3,4-dimethoxyphenyl)-1-(3-(2-oxo-2-(5-oxopentylamino)ethoxy)phenyl)propyl) 1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate

Base Information

• Chemical Name: (S)-((R)-3-(3,4-dimethoxyphenyl)-1-(3-(2-oxo-2-(5-oxopentylamino)ethoxy)phenyl)propyl) 1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate
• CAS No.: 1228544-21-5
• Molecular Formula: C₃₇H₅₀N₂O₉
• Molecular Weight: 666.812

Synonyms:(S)-((R)-3-(3,4-dimethoxyphenyl)-1-(3-(2-oxo-2-(5-oxopentylamino)ethoxy)phenyl)propyl) 1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate

Chemical Property of (S)-((R)-3-(3,4-dimethoxyphenyl)-1-(3-(2-oxo-2-(5-oxopentylamino)ethoxy)phenyl)propyl) 1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate

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Technology Process of (S)-((R)-3-(3,4-dimethoxyphenyl)-1-(3-(2-oxo-2-(5-oxopentylamino)ethoxy)phenyl)propyl) 1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate

There total 1 articles about (S)-((R)-3-(3,4-dimethoxyphenyl)-1-(3-(2-oxo-2-(5-oxopentylamino)ethoxy)phenyl)propyl) 1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C37H52N2O9 (1228544-20-4) → (S)-((R)-3-(3,4-dimethoxyphenyl)-1-(3-(2-oxo-2-(5-oxopentylamino)ethoxy)phenyl)propyl) 1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate (1228544-21-5)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane; at 20 ℃;

Reference yield:

(S)-((R)-3-(3,4-dimethoxyphenyl)-1-(3-(2-oxo-2-(5-oxopentylamino)ethoxy)phenyl)propyl) 1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate (1228544-21-5) + meropenem (96036-03-2) → (4R,5S,6S)-3-((3S,5S)-1-(5-(2-(3-((R)-3-(3,4-dimethoxyphenyl)-1-((S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carbonyloxy)propyl)phenoxy)acetamido)pentyl)-5-(dimethylcarbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (1228544-08-8)

Guidance literature:

With sodium cyanoborohydride; acetic acid; In tetrahydrofuran; at 0 - 20 ℃;

upstream raw materials:

C₃₇H₅₂N₂O₉

Downstream raw materials:

(4R,5S,6S)-3-((3S,5S)-1-(5-(2-(3-((R)-3-(3,4-dimethoxyphenyl)-1-((S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carbonyloxy)propyl)phenoxy)acetamido)pentyl)-5-(dimethylcarbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

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