Technology Process of 2-(2-propen-1-yl)-2-bromoethynylbenzene
There total 4 articles about 2-(2-propen-1-yl)-2-bromoethynylbenzene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
carbon tetrabromide; triphenylphosphine;
In
dichloromethane;
for 0.333333h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: tetr-butyllithium / diethyl ether / 1.) -78 deg C, 20 min, 2.) 25 deg C, 12 h
2: 78 percent / tetrabutylammonium fluoride / tetrahydrofuran; H2O / 0 °C
3: 47 percent / CBr4, triphenylphosphine / CH2Cl2 / 0.33 h / Ambient temperature
With
carbon tetrabromide; tetrabutyl ammonium fluoride; tert.-butyl lithium; triphenylphosphine;
In
tetrahydrofuran; diethyl ether; dichloromethane; water;
DOI:10.1021/jo00075a045
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 89 percent / Et3N
2: tetr-butyllithium / diethyl ether / 1.) -78 deg C, 20 min, 2.) 25 deg C, 12 h
3: 78 percent / tetrabutylammonium fluoride / tetrahydrofuran; H2O / 0 °C
4: 47 percent / CBr4, triphenylphosphine / CH2Cl2 / 0.33 h / Ambient temperature
With
carbon tetrabromide; tetrabutyl ammonium fluoride; tert.-butyl lithium; triethylamine; triphenylphosphine;
In
tetrahydrofuran; diethyl ether; dichloromethane; water;
DOI:10.1021/jo00075a045
