(S)-trifluoromethanesulfonic acid 4-[2-tert-butoxycarbonylamino-3-((S)-2-cyanopyrrolidin-1-yl)-3-oxopropyl]-3-fluorophenyl ester

Base Information

Chemical Name:(S)-trifluoromethanesulfonic acid 4-[2-tert-butoxycarbonylamino-3-((S)-2-cyanopyrrolidin-1-yl)-3-oxopropyl]-3-fluorophenyl ester
CAS No.:1245201-44-8
Molecular Formula:C₂₀H₂₃F₄N₃O₆S
Molecular Weight:509.479
Hs Code.:

Synonyms:(S)-trifluoromethanesulfonic acid 4-[2-tert-butoxycarbonylamino-3-((S)-2-cyanopyrrolidin-1-yl)-3-oxopropyl]-3-fluorophenyl ester

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Chemical Property of (S)-trifluoromethanesulfonic acid 4-[2-tert-butoxycarbonylamino-3-((S)-2-cyanopyrrolidin-1-yl)-3-oxopropyl]-3-fluorophenyl ester

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Technology Process of (S)-trifluoromethanesulfonic acid 4-[2-tert-butoxycarbonylamino-3-((S)-2-cyanopyrrolidin-1-yl)-3-oxopropyl]-3-fluorophenyl ester

There total 1 articles about (S)-trifluoromethanesulfonic acid 4-[2-tert-butoxycarbonylamino-3-((S)-2-cyanopyrrolidin-1-yl)-3-oxopropyl]-3-fluorophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1245201-43-7
(S)-trifluoromethanesulfonic acid 4-[2-tert-butoxycarbonylamino-3-((S)-2-carbamoylpyrrolidin-1-yl)-3-oxopropyl]-3-fluorophenyl ester

: 1245201-44-8
(S)-trifluoromethanesulfonic acid 4-[2-tert-butoxycarbonylamino-3-((S)-2-cyanopyrrolidin-1-yl)-3-oxopropyl]-3-fluorophenyl ester

Guidance literature:: With pyridine; trifluoroacetic anhydride; In tetrahydrofuran; at 0 ℃; for 0.0833333h;

Reference yield:

: 1245079-51-9
4-{1-[5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridin-2-yloxy]ethyl}-piperidine-1-carboxylic acid isopropyl ester

: 1245201-44-8
(S)-trifluoromethanesulfonic acid 4-[2-tert-butoxycarbonylamino-3-((S)-2-cyanopyrrolidin-1-yl)-3-oxopropyl]-3-fluorophenyl ester

: 1245201-87-9
(S)-4-[1-(5-{4-[2-tert-butoxycarbonylamino-3-((S)-2-cyanopyrrolidin-1-yl)-3-oxopropyl]-3-fluorophenyl}pyridin-2-yloxy)ethyl]piperidine-1-carboxylic acid isopropyl ester

Guidance literature:: With triethylamine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In water; N,N-dimethyl-formamide; at 80 ℃; for 1h; Microwave irradiation;

Reference yield:

: 1245201-25-5
4-[5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridin-2-yloxy]piperidine-1-carboxylic acid isopropyl ester

: 1245201-44-8
(S)-trifluoromethanesulfonic acid 4-[2-tert-butoxycarbonylamino-3-((S)-2-cyanopyrrolidin-1-yl)-3-oxopropyl]-3-fluorophenyl ester

: 1245202-09-8
(S)-4-(5-{4-[2-tert-butoxycarbonylamino-3-((S)-2-cyanopyrrolidin-1-yl)-3-oxopropyl]-3-fluorophenyl}pyridine-2-yloxy)piperidine-1-carboxylic acid isopropyl ester

Guidance literature:: With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; at 75 ℃; for 0.5h; Microwave irradiation; Inert atmosphere;