5((E)-3-bromoprop-1-enyl)-1,2,3-trimethoxybenzene

Base Information

• Chemical Name: 5((E)-3-bromoprop-1-enyl)-1,2,3-trimethoxybenzene
• CAS No.: 1115589-46-2
• Molecular Formula: C₁₂H₁₅BrO₃
• Molecular Weight: 287.153
• Mol file: 1115589-46-2.mol

Synonyms:5((E)-3-bromoprop-1-enyl)-1,2,3-trimethoxybenzene

Chemical Property of 5((E)-3-bromoprop-1-enyl)-1,2,3-trimethoxybenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5((E)-3-bromoprop-1-enyl)-1,2,3-trimethoxybenzene

There total 1 articles about 5((E)-3-bromoprop-1-enyl)-1,2,3-trimethoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-ol (1504-56-9) → 5((E)-3-bromoprop-1-enyl)-1,2,3-trimethoxybenzene (1115589-46-2)

Guidance literature:

With phosphorus tribromide; In tetrahydrofuran; diethyl ether; at 0 - 20 ℃; for 18h;

Reference yield: 65.0%

5((E)-3-bromoprop-1-enyl)-1,2,3-trimethoxybenzene (1115589-46-2) + (E)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-ol (1504-56-9) → 5,5'-((1E,1'E)-oxybis(prop-1-ene-3,1-diyl))bis(1,2,3-trimethoxybenzene)

Guidance literature:

(E)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-ol; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 0.5h;

5((E)-3-bromoprop-1-enyl)-1,2,3-trimethoxybenzene; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 24h;

DOI:10.1002/anie.202007548

Reference yield:

5((E)-3-bromoprop-1-enyl)-1,2,3-trimethoxybenzene (1115589-46-2) → (±)-aglacin B

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / mineral oil; tetrahydrofuran / 0.5 h / 0 - 20 °C

1.2: 24 h / 0 - 20 °C

2.1: thiophenol; 10-methyl-9-(2,4,6-trimethylphenyl) acridinium tetrafluoroborate / dichloromethane / 36 h / 23 °C / Sealed tube; Inert atmosphere; Irradiation

With 10-methyl-9-(2,4,6-trimethylphenyl) acridinium tetrafluoroborate; sodium hydride; thiophenol; In tetrahydrofuran; dichloromethane; mineral oil;

DOI:10.1002/anie.202007548

upstream raw materials:

(E)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-ol

Downstream raw materials:

Br^(1-)*C₂₄H₄₂O₃P⁽¹⁺⁾

Refernces

• 1、 -. "ASYMMETRIC ONE- AND TWO-PHOTON FLUOROPHORES FOR SIMULTANEOUS DETECTION OF MULTIPLE ANALYTES USING A COMMON EXCITATION SOURCE". Page/Page column sheet 4; 11. . Retrieved 2009/03/07.