(E)-4-methyl-N-(4-methylpenta-2,3-dien-1-yl)-N-(penta-2,4-dien-1-yl)benzenesulfonamide

Base Information

• Chemical Name: (E)-4-methyl-N-(4-methylpenta-2,3-dien-1-yl)-N-(penta-2,4-dien-1-yl)benzenesulfonamide
• CAS No.: 1152437-69-8
• Molecular Formula: C₁₈H₂₃NO₂S
• Molecular Weight: 317.452
• Mol file: 1152437-69-8.mol

Synonyms:(E)-4-methyl-N-(4-methylpenta-2,3-dien-1-yl)-N-(penta-2,4-dien-1-yl)benzenesulfonamide

Chemical Property of (E)-4-methyl-N-(4-methylpenta-2,3-dien-1-yl)-N-(penta-2,4-dien-1-yl)benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-4-methyl-N-(4-methylpenta-2,3-dien-1-yl)-N-(penta-2,4-dien-1-yl)benzenesulfonamide

There total 2 articles about (E)-4-methyl-N-(4-methylpenta-2,3-dien-1-yl)-N-(penta-2,4-dien-1-yl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

4-methylpenta-2,3-dien-1-ol (2425-45-8) + (E)-4-methyl-N-(penta-2,4-dien-1-yl)benzenesulfonamide (136573-40-5) → (E)-4-methyl-N-(4-methylpenta-2,3-dien-1-yl)-N-(penta-2,4-dien-1-yl)benzenesulfonamide (1152437-69-8)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 25 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ja905415r

Reference yield:

(E)-4-methyl-N-(penta-2,4-dien-1-yl)benzenesulfonamide (136573-40-5) + 4-methyl-2,3-pentadienyl methanesulfonate (656253-67-7) → (E)-4-methyl-N-(4-methylpenta-2,3-dien-1-yl)-N-(penta-2,4-dien-1-yl)benzenesulfonamide (1152437-69-8)

Guidance literature:

(E)-4-methyl-N-(penta-2,4-dien-1-yl)benzenesulfonamide; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

4-methyl-2,3-pentadienyl methanesulfonate; With sodium iodide; In tetrahydrofuran; dimethyl sulfoxide; at 0 - 20 ℃; Inert atmosphere;

Reference yield: 93.0%

(E)-4-methyl-N-(4-methylpenta-2,3-dien-1-yl)-N-(penta-2,4-dien-1-yl)benzenesulfonamide (1152437-69-8) → (3aS,7aR)-4-(propan-2-ylidene)-2-(p-tosyl)-2,3,3a,4,5,7a-hexahydro-1H-isoindole (1186031-21-9)

Guidance literature:

With silver hexafluoroantimonate; C₆₄H₄₆AuClNO₂P; In dichloromethane; at -15 ℃; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1021/ja905415r

upstream raw materials:

(E)-4-methyl-N-(penta-2,4-dien-1-yl)benzenesulfonamide

4-methyl-2,3-pentadienyl methanesulfonate

4-methylpenta-2,3-dien-1-ol

Downstream raw materials:

C₁₈H₂₃NO₂S

C₁₈H₂₃NO₂S

C₁₉H₂₇NO₃S

N-((E)-4-methoxy-4-methylpent-2-enyl)-4-methyl-N-(-penta-2,4-dienyl)benzenesulfonamide