Melinamide

Base Information

Chemical Name:Melinamide
CAS No.:14417-88-0
Molecular Formula:C26H41 N O
Molecular Weight:383.618
Hs Code.:
UNII:JJ07049A84
ChEMBL ID:CHEMBL64379
DSSTox Substance ID:DTXSID9048809
NCI Thesaurus Code:C87732
Nikkaji Number:J3.443F
Wikidata:Q27281525
Mol file:14417-88-0.mol

Synonyms:melinamide;N-(2-methylbenzyl)linoleamide;N-(2-methylbenzyl)linoleamide, (+)-isomer;N-(2-methylbenzyl)linoleamide, (S-(Z,Z))-isomer;N-(2-methylbenzyl)linoleamide, (Z,Z)-(+-)-isomer;N-(alpha-methylbenzyl)-cis,cis-octadeca-9,12-dienamide;N-(alpha-methylbenzyl)linoleamide;N-(o-methylbenzyl)linoleamide

Suppliers and Price of Melinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
MELINAMIDE 95.00%
5MG
$ 495.95

Total 9 raw suppliers

Chemical Property of Melinamide

Chemical Property:

Vapor Pressure:1.27E-11mmHg at 25°C
Melting Point:<4°
Refractive Index:nD23 1.5050; nD30 1.4863
Boiling Point:537.4°Cat760mmHg
PKA:15.56±0.46(Predicted)
Flash Point:333.3°C
PSA：29.10000
Density:0.928g/cm³
LogP:8.06820
XLogP3:8.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:16
Exact Mass:383.318814931
Heavy Atom Count:28
Complexity:420

Purity/Quality:

99%, ^*data from raw suppliers

MELINAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Low toxicity by ingestion.
Hazard Codes:Low toxicity by ingestion.

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCC=CCC=CCCCCCCCC(=O)NC(C)C1=CC=CC=C1
Isomeric SMILES:CCCCC/C=C\C/C=C\CCCCCCCC(=O)NC(C)C1=CC=CC=C1
Description Melinamide is an amide of linoleic acid useful in the treatment of hypercholesterolemia. The mechanism of action of melinamide appears to involve the inhibition of cholesterol absorption from the gastrointestinal tract.
Uses Melinamide is used in the synthesis and biological screening of library of macamides as TNF alpha inhibitors with greater anti-inflammatory activity in human monocytic cell.

Technology Process of Melinamide

There total 2 articles about Melinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%